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Publications

Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study.

Pham TT, Nimptsch K, Papadimitriou N, et al. Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study. Journal of cancer research and clinical oncology. 2023. doi:10.1007/s00432-023-05193-0

Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.

Cheong JG, Ravishankar A, Sharma S, et al. Epigenetic memory of coronavirus infection in innate immune cells and their progenitors. Cell. 2023. doi:10.1016/j.cell.2023.07.019

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function.

Larange A, Takazawa I, Kakugawa K, et al. A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function. Immunity. 2023. doi:10.1016/j.immuni.2023.07.017

Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors.

Groves A, Ward A, Li YY, et al. Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors. Pediatric blood & cancer. 2023:e30643. doi:10.1002/pbc.30643

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.

Miller PG, Sperling AS, Mayerhofer C, et al. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy. Blood. 2023. doi:10.1182/blood.2023020331

Systematic evaluation of genome sequencing for the diagnostic assessment of autism spectrum disorder and fetal structural anomalies.

Lowther C, Valkanas E, Giordano JL, et al. Systematic evaluation of genome sequencing for the diagnostic assessment of autism spectrum disorder and fetal structural anomalies. American journal of human genetics. 2023. doi:10.1016/j.ajhg.2023.07.010

Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.

O’Meara TR, Nanishi E, McGrath ME, et al. Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance. The Journal of allergy and clinical immunology. 2023. doi:10.1016/j.jaci.2023.06.031

A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.

Akbari P, Vuckovic D, Stefanucci L, et al. A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology. Nature communications. 2023;14(1):5023. doi:10.1038/s41467-023-40679-y

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance.

Naeem A, Utro F, Wang Q, et al. Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance. Blood advances. 2023;7(9):1929-1943. doi:10.1182/bloodadvances.2022008447

Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness.

Li Y, Lih TSM, Dhanasekaran SM, et al. Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness. Cancer cell. 2023;41(1):139-163.e17. doi:10.1016/j.ccell.2022.12.001