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Publications

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases.

Truong B, Hull LE, Ruan Y, et al. Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases. Cell genomics. 2024:100523. doi:10.1016/j.xgen.2024.100523

Investigating the Roles and Responsibilities of Institutional Signing Officials After Data Sharing Policy Reform for Federally Funded Research in the United States: National Survey.

Baek J, Lawson J, Rahimzadeh V. Investigating the Roles and Responsibilities of Institutional Signing Officials After Data Sharing Policy Reform for Federally Funded Research in the United States: National Survey. JMIR formative research. 2024;8:e49822. doi:10.2196/49822

SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease.

Strausz S, Abner E, Blacker G, et al. SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease. Nature communications. 2024;15(1):2041. doi:10.1038/s41467-024-45983-9

Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial.

Zañudo JGT, Barroso-Sousa R, Jain E, et al. Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial. Nature communications. 2024;15(1):2446. doi:10.1038/s41467-024-45835-6

Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy.

Chen JH, Nieman LT, Spurrell M, et al. Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy. Nature immunology. 2024. doi:10.1038/s41590-024-01792-2

A visual-language foundation model for computational pathology.

Lu MY, Chen B, Williamson DFK, et al. A visual-language foundation model for computational pathology. Nature medicine. 2024. doi:10.1038/s41591-024-02856-4

Towards a general-purpose foundation model for computational pathology.

Chen RJ, Ding T, Lu MY, et al. Towards a general-purpose foundation model for computational pathology. Nature medicine. 2024. doi:10.1038/s41591-024-02857-3

Multicenter integrated analysis of noncoding CRISPRi screens.

Yao D, Tycko J, Oh JW, et al. Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods. 2024. doi:10.1038/s41592-024-02216-7

APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.

Jackson RJ, Keiser MS, Meltzer JC, et al. APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease. Molecular therapy : the journal of the American Society of Gene Therapy. 2024. doi:10.1016/j.ymthe.2024.03.024

Patterns of reproductive health in inflammatory rheumatic diseases and other immune-mediated diseases: a nationwide registry study.

Kerola AM, Palomäki A, Laivuori H, et al. Patterns of reproductive health in inflammatory rheumatic diseases and other immune-mediated diseases: a nationwide registry study. Rheumatology (Oxford, England). 2024. doi:10.1093/rheumatology/keae122