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Publications

VIBRANT: spectral profiling for single-cell drug responses.

Liu X, Shi L, Zhao Z, Shu J, Min W. VIBRANT: spectral profiling for single-cell drug responses. Nature methods. 2024. doi:10.1038/s41592-024-02185-x

The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.

Sumida TS, Cheru NT, Hafler DA. The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases. Nature reviews. Immunology. 2024. doi:10.1038/s41577-024-00994-x

Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.

Lennon NJ, Kottyan LC, Kachulis C, et al. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature medicine. 2024. doi:10.1038/s41591-024-02796-z

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2.

Pérez-Jurado LA, Cáceres A, Balagué-Dobón L, et al. Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2. Communications biology. 2024;7(1):202. doi:10.1038/s42003-024-05805-6

The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities.

Venner E, Patterson K, Kalra D, et al. The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities. Communications biology. 2024;7(1):174. doi:10.1038/s42003-023-05708-y

Cell Painting Gallery: an open resource for image-based profiling.

Weisbart E, Kumar A, Arevalo J, Carpenter AE, Cimini BA, Singh S. Cell Painting Gallery: an open resource for image-based profiling. ArXiv. 2024.

Harmonizing the Generation and Pre-publication Stewardship of FAIR Image data.

Bialy N, Alber F, Andrews B, et al. Harmonizing the Generation and Pre-publication Stewardship of FAIR Image data. ArXiv. 2024.

Genome-wide association analysis of composite sleep health scores in 413,904 individuals.

Goodman MO, Faquih T, Paz V, et al. Genome-wide association analysis of composite sleep health scores in 413,904 individuals. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.02.02.24302211

Potential for Bridging Treatment Gaps in Cardiovascular Health in Asia With Inclusive Clinical Trials.

Patel AP. Potential for Bridging Treatment Gaps in Cardiovascular Health in Asia With Inclusive Clinical Trials. JACC. Asia. 2024;4(2):135-137. doi:10.1016/j.jacasi.2023.11.008

Sex Differences in the Association of Multiethnic Genome-Wide Blood Pressure Polygenic Risk Score With Population-Level Systolic Blood Pressure Trajectories.

Shetty NS, Pampana A, Patel N, et al. Sex Differences in the Association of Multiethnic Genome-Wide Blood Pressure Polygenic Risk Score With Population-Level Systolic Blood Pressure Trajectories. Circulation. Genomic and precision medicine. 2024:e004515. doi:10.1161/CIRCGEN.123.004515