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Publications

Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.

Cadinu P, Sivanathan KN, Misra A, et al. Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.05.08.539701

Hidden protein-altering variants influence diverse human phenotypes.

Hujoel MLA, Handsaker RE, Sherman MA, et al. Hidden protein-altering variants influence diverse human phenotypes. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.06.07.544066

Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.

Wen C, Margolis M, Dai R, et al. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.03.03.23286706

Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders.

Der Li Y, Ma MW, Hassan MM, et al. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.14.528208

DNA methylation signatures of early life adversity are exposure-dependent in wild baboons.

Anderson JA, Lin D, Lea AJ, et al. DNA methylation signatures of early life adversity are exposure-dependent in wild baboons. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.06.05.542485

Insights from a genome-wide truth set of tandem repeat variation.

Weisburd B, Tiao G, Rehm HL. Insights from a genome-wide truth set of tandem repeat variation. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.05.05.539588

The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales.

Cartagena AJ, Taylor KL, Smith JT, et al. The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.05.23.541813

Association of Clonal Hematopoiesis of Indeterminate Potential with Incident Heart Failure with Preserved Ejection Fraction.

Reiner AP, Roberts MB, Honigberg MC, et al. Association of Clonal Hematopoiesis of Indeterminate Potential with Incident Heart Failure with Preserved Ejection Fraction. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.06.07.23291038

Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypes.

Zekavat SM, Jorshery SD, Shweikh Y, et al. Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypes. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.05.16.23290063

Rapid and Multiplexed Nucleic Acid Detection using Programmable Aptamer-Based RNA Switches.

Yan Z, Tang AA, Eshed A, et al. Rapid and Multiplexed Nucleic Acid Detection using Programmable Aptamer-Based RNA Switches. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.06.02.23290873