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Publications

SpheroScan: A User-Friendly Deep Learning Tool for Spheroid Image Analysis.

Akshay A, Katoch M, Abedi M, et al. SpheroScan: A User-Friendly Deep Learning Tool for Spheroid Image Analysis. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.06.28.533479

Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements.

Hu Y, Ma S, Kartha VK, et al. Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.28.533945

SARS-CoV-2 virologic rebound with nirmatrelvir-ritonavir therapy.

Edelstein GE, Boucau J, Uddin R, et al. SARS-CoV-2 virologic rebound with nirmatrelvir-ritonavir therapy. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.06.23.23288598

Shared and distinct ultra-rare genetic risk for diverse epilepsies: A whole-exome sequencing study of 54,423 individuals across multiple genetic ancestries.

Chen S, Neale BM, Berkovic SF, . Shared and distinct ultra-rare genetic risk for diverse epilepsies: A whole-exome sequencing study of 54,423 individuals across multiple genetic ancestries. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.02.22.23286310

Developing a Phenotype Risk Score for Tic Disorders in a Large, Clinical Biobank.

Miller-Fleming TW, Allos A, Gantz E, et al. Developing a Phenotype Risk Score for Tic Disorders in a Large, Clinical Biobank. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.02.21.23286253

Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.

Gibson WJ, Sadagopan A, Shoba VM, Choudhary A, Meyerson M, Schreiber SL. Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.07.07.548101

S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness.

Yurkovetskiy L, Egri S, Kurhade C, et al. S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.30.535005

Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis.

Akshay A, Katoch M, Shekarchizadeh N, et al. Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.07.04.546825

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases.

Truong B, Hull LE, Ruan Y, et al. Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.02.21.23286110

Structurally divergent and recurrently mutated regions of primate genomes.

Mao Y, Harvey WT, Porubsky D, et al. Structurally divergent and recurrently mutated regions of primate genomes. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.07.531415