Publications

Cross-kingdom anti-inflammatory effects of fungal melanin on airway epithelium by post-translational blockade of chemokine secretion.

Reedy JL, Crossen AJ, Ward RA, et al. Cross-kingdom anti-inflammatory effects of fungal melanin on airway epithelium by post-translational blockade of chemokine secretion. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.28.534632

Contextualizing protein representations using deep learning on protein networks and single-cell data.

Li MM, Huang Y, Sumathipala M, et al. Contextualizing protein representations using deep learning on protein networks and single-cell data. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.07.18.549602

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.

Lee DSM, Cardone KM, Zhang DY, et al. Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.07.16.23292724

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.

Lee DSM, Cardone KM, Zhang DY, et al. Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.07.16.23292724

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.

Yuan K, Longchamps RJ, Pardiñas AF, et al. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.01.07.23284293

Proteogenomic integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis.

Prapiadou S, Živković L, Thorand B, et al. Proteogenomic integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.03.24.23287543

Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.

Wen C, Margolis M, Dai R, et al. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.03.03.23286706

The genetic architecture of changes in adiposity during adulthood.

Venkatesh SS, Ganjgahi H, Palmer DS, et al. The genetic architecture of changes in adiposity during adulthood. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.01.09.23284364

A gene pathogenicity tool 'GenePy' identifies missed biallelic diagnoses in the 100,000 Genomes Project.

Seaby EG, Leggatt G, Cheng G, et al. A gene pathogenicity tool ’GenePy’ identifies missed biallelic diagnoses in the 100,000 Genomes Project. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.03.21.23287545

Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain.

Ganz J, Luquette LJ, Bizzotto S, et al. Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.01.14.523958

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Publications

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