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Publications

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease.

Lim K, Rutherford EN, Sun D, et al. A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.08.30.555522

Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification.

Ryu J, Barkal S, Yu T, et al. Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.09.08.23295253

Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis.

Uddin MM, Saadatagah S, Niroula A, et al. Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.09.05.23295093

Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning.

Laubscher E, Wang XJ, Razin N, et al. Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.09.03.556122

Leukemia circulation kinetics revealed through blood exchange method.

Miller AB, Langenbucher A, Rodriguez FH, et al. Leukemia circulation kinetics revealed through blood exchange method. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.09.03.556043

Pervasive mislocalization of pathogenic coding variants underlying human disorders.

Lacoste J, Haghighi M, Haider S, et al. Pervasive mislocalization of pathogenic coding variants underlying human disorders. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.09.05.556368

Episymbiotic bacterium induces intracellular lipid droplet production in its host bacteria.

Dong PT, Tian J, Kobayashi-Kirschvink KJ, et al. Episymbiotic bacterium induces intracellular lipid droplet production in its host bacteria. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.09.06.556576

Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores - a new resource for diabetes precision medicine.

Szczerbiński L, Mandla R, Schroeder P, et al. Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores - a new resource for diabetes precision medicine. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.09.05.23295061

Pleiotropic Genetic Effects between Multiple Sclerosis and Musculoskeletal Traits.

Jeong S, Tsai MJ, Shen C, Hsu YH. Pleiotropic Genetic Effects between Multiple Sclerosis and Musculoskeletal Traits. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.09.12.23295444

Engineering synthetic phosphorylation signaling networks in human cells.

Yang X, Rocks JW, Jiang K, et al. Engineering synthetic phosphorylation signaling networks in human cells. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.09.11.557100