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Publications

Genic constraint against nonsynonymous variation across the mouse genome.

Powell G, Simon MM, Pulit S, Mallon AM, Lindgren CM. Genic constraint against nonsynonymous variation across the mouse genome. BMC genomics. 2023;24(1):562. doi:10.1186/s12864-023-09637-2

Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma.

Estabrooks T, Gurinovich A, Pietruska J, et al. Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma. Veterinary and comparative oncology. 2023. doi:10.1111/vco.12925

Manipulating mitochondrial electron flow enhances tumor immunogenicity.

Mangalhara KC, Varanasi SK, Johnson MA, et al. Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science (New York, N.Y.). 2023;381(6664):1316-1323. doi:10.1126/science.abq1053

The Significance of Hematuria in Podocytopathies.

Marchel D, Trachtman H, Larkina M, et al. The Significance of Hematuria in Podocytopathies. Clinical journal of the American Society of Nephrology : CJASN. 2023. doi:10.2215/CJN.0000000000000309

Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders.

Lizano P, Pong S, Santarriaga S, Bannai D, Karmacharya R. Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders. Molecular psychiatry. 2023. doi:10.1038/s41380-023-02255-0

Transgenic ferret models define pulmonary ionocyte diversity and function.

Yuan F, Gasser GN, Lemire E, et al. Transgenic ferret models define pulmonary ionocyte diversity and function. Nature. 2023. doi:10.1038/s41586-023-06549-9

Proteomic architecture of frailty across the spectrum of cardiovascular disease.

Perry AS, Zhao S, Gajjar P, et al. Proteomic architecture of frailty across the spectrum of cardiovascular disease. Aging cell. 2023. doi:10.1111/acel.13978

Single-Cell RNA Sequencing Reveals Cellular Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress.

Salazar-Martín AG, Kalluri AS, Villanueva MA, et al. Single-Cell RNA Sequencing Reveals Cellular Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress. Arteriosclerosis, thrombosis, and vascular biology. 2023. doi:10.1161/ATVBAHA.123.319283

Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses.

Kahraman S, Shibue K, De Jesus DF, et al. Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses. eLife. 2023;12. doi:10.7554/eLife.85056

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.

Nyman J, Denize T, Bakouny Z, et al. Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states. Cell reports. Medicine. 2023;4(9):101189. doi:10.1016/j.xcrm.2023.101189