Brown JI, Wang P, Wong AYL, et al. Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity. Metabolites. 2023;13(2). doi:10.3390/metabo13020151
Publications
Ament SA, Adkins RS, Carter R, et al. The Neuroscience Multi-Omic Archive: a BRAIN Initiative resource for single-cell transcriptomic and epigenomic data from the mammalian brain. Nucleic acids research. 2023;51(D1):D1075-D1085. doi:10.1093/nar/gkac962
Sato S, Gillette M, de Santiago P, et al. LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma. Scientific reports. 2023;13(1):1537. doi:10.1038/s41598-023-28840-5
Orsi D, Ferrara S, Siegel S, et al. Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. Bioorganic & medicinal chemistry. 2023;78:117130. doi:10.1016/j.bmc.2022.117130
Agrawal S, Klarqvist M, Diamant N, et al. BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases. Nature communications. 2023;14(1):266. doi:10.1038/s41467-022-35704-5
Lu D, Ellegast J, Ross K, et al. The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology. 2023. doi:10.1038/s41556-022-01059-8
Pietiläinen O, Trehan A, Meyer D, et al. Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons. Cell reports. 2023;42(1):111988. doi:10.1016/j.celrep.2022.111988
Tian J. Combined PD-1, BRAF and MEK inhibition in BRAF colorectal cancer: a phase 2 trial. Nature medicine. 2023. doi:10.1038/s41591-022-02181-8
Kong L, Pokatayev V, Lefkovith A, et al. The landscape of immune dysregulation in Crohn’s disease revealed through single-cell transcriptomic profiling in the ileum and colon. Immunity. 2023. doi:10.1016/j.immuni.2023.01.002
Sun Y, Revach OY, Anderson S, et al. Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature. 2023. doi:10.1038/s41586-023-05704-6