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Publications

Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.

Pikman Y, Ocasio-Martinez N, Alexe G, et al. Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy. Leukemia. 2021. doi:10.1038/s41375-021-01361-8

Circulating blood metabolite trajectories and risk of rheumatoid arthritis among military personnel in the Department of Defense Biorepository.

Costenbader KH, DiIorio M, Chu SH, et al. Circulating blood metabolite trajectories and risk of rheumatoid arthritis among military personnel in the Department of Defense Biorepository. Annals of the rheumatic diseases. 2021;80(8):989-996. doi:10.1136/annrheumdis-2020-219682

Metabolite Biomarkers of CKD Progression in Children.

Denburg MR, Xu Y, Abraham AG, et al. Metabolite Biomarkers of CKD Progression in Children. Clinical journal of the American Society of Nephrology : CJASN. 2021;16(8):1178-1189. doi:10.2215/CJN.00220121

Cycling cancer persister cells arise from lineages with distinct programs.

Oren Y, Tsabar M, Cuoco MS, et al. Cycling cancer persister cells arise from lineages with distinct programs. Nature. 2021;596(7873):576-582. doi:10.1038/s41586-021-03796-6

Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent.

Haslam DE, Liang L, Wang DD, et al. Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent. BMJ open diabetes research & care. 2021;9(1). doi:10.1136/bmjdrc-2021-002298

Metabolic modeling of single Th17 cells reveals regulators of autoimmunity.

Wagner A, Wang C, Fessler J, et al. Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell. 2021;184(16):4168-4185.e21. doi:10.1016/j.cell.2021.05.045

PRICKLE2 revisited-further evidence implicating PRICKLE2 in neurodevelopmental disorders.

Bayat A, Iqbal S, Borredy K, et al. PRICKLE2 revisited-further evidence implicating PRICKLE2 in neurodevelopmental disorders. Eur J Hum Genet. 2021;29(8):1235-1244. doi:10.1038/s41431-021-00912-y

The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes.

Clemons PA, Bittker JA, Wagner FF, et al. The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes. SLAS Discov. 2021;26(7):855-861. doi:10.1177/24725552211019410

Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants.

de Puig H, Lee RA, Najjar D, et al. Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants. Sci Adv. 2021;7(32). doi:10.1126/sciadv.abh2944

Epigenetic scars of CD8 T cell exhaustion persist after cure of chronic infection in humans.

Yates KB, Tonnerre P, Martin GE, et al. Epigenetic scars of CD8 T cell exhaustion persist after cure of chronic infection in humans. Nat Immunol. 2021;22(8):1020-1029. doi:10.1038/s41590-021-00979-1