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Publications

Gut microbiome ADP-ribosyltransferases are widespread phage-encoded fitness factors.

Brown EM, Arellano-Santoyo H, Temple ER, et al. Gut microbiome ADP-ribosyltransferases are widespread phage-encoded fitness factors. Cell Host Microbe. 2021;29(9):1351-1365.e11. doi:10.1016/j.chom.2021.07.011

Whole-genome sequencing of multiple isolates of Puccinia triticina reveals asexual lineages evolving by recurrent mutations.

Fellers JP, Sakthikumar S, He F, et al. Whole-genome sequencing of multiple isolates of Puccinia triticina reveals asexual lineages evolving by recurrent mutations. G3 (Bethesda). 2021;11(9). doi:10.1093/g3journal/jkab219

CellProfiler Analyst 3.0: Accessible data exploration and machine learning for image analysis.

Stirling DR, Carpenter AE, Cimini BA. CellProfiler Analyst 3.0: Accessible data exploration and machine learning for image analysis. Bioinformatics. 2021. doi:10.1093/bioinformatics/btab634

The challenges in treating Embryonal Tumors with Multilayered Rosettes (ETMR) and other infant brain tumors.

Bandopadhayay P, Chi SN. The challenges in treating Embryonal Tumors with Multilayered Rosettes (ETMR) and other infant brain tumors. Neuro Oncol. 2021. doi:10.1093/neuonc/noab206

Telomerase as a therapeutic target in glioblastoma.

Aquilanti E, Kageler L, Wen PY, Meyerson M. Telomerase as a therapeutic target in glioblastoma. Neuro Oncol. 2021. doi:10.1093/neuonc/noab203

Molecular basis for substrate recruitment to the PRMT5 methylosome.

Mulvaney KM, Blomquist C, Acharya N, et al. Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol Cell. 2021;81(17):3481-3495.e7. doi:10.1016/j.molcel.2021.07.019

GRAFIMO: Variant and haplotype aware motif scanning on pangenome graphs.

Tognon M, Bonnici V, Garrison E, Giugno R, Pinello L. GRAFIMO: Variant and haplotype aware motif scanning on pangenome graphs. PLoS computational biology. 2021;17(9):e1009444. doi:10.1371/journal.pcbi.1009444

Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.

Koga Y, Hoang E, Park Y, et al. Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. Journal of the American Chemical Society. 2021;143(34):13473-13477. doi:10.1021/jacs.1c05146

A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function.

Honecker J, Weidlich D, Heisz S, et al. A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function. International journal of obesity (2005). 2021;45(9):2108-2117. doi:10.1038/s41366-021-00883-6

Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.

Malone CF, Dharia N V, Kugener G, et al. Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer. Cancer discovery. 2021;11(9):2282-2299. doi:10.1158/2159-8290.CD-20-1213