SÅ‚abicki M, Kozicka Z, Petzold G, et al. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature. 2020. doi:10.1038/s41586-020-2374-x
Publications
de Boer CG, Ray JP, Hacohen N, Regev A. MAUDE: inferring expression changes in sorting-based CRISPR screens. Genome Biol. 2020;21(1):134. doi:10.1186/s13059-020-02046-8
Cho KF, Branon TC, Rajeev S, et al. Split-TurboID enables contact-dependent proximity labeling in cells. Proc Natl Acad Sci U S A. 2020;117(22):12143-12154. doi:10.1073/pnas.1919528117
Morrison MS, Podracky CJ, Liu DR. The developing toolkit of continuous directed evolution. Nat Chem Biol. 2020;16(6):610-619. doi:10.1038/s41589-020-0532-y
Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK. Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell. Elife. 2020;9. doi:10.7554/eLife.49178
Abel HJ, Larson DE, Regier AA, et al. Mapping and characterization of structural variation in 17,795 human genomes. Nature. 2020. doi:10.1038/s41586-020-2371-0
Marshall CR, Bick D, Belmont JW, et al. The Medical Genome Initiative: moving whole-genome sequencing for rare disease diagnosis to the clinic. Genome Med. 2020;12(1):48. doi:10.1186/s13073-020-00748-z
Knevel R, le Cessie S, Terao CC, et al. Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis. Sci Transl Med. 2020;12(545). doi:10.1126/scitranslmed.aay1548
Wang Q, Pierce-Hoffman E, Cummings BB, et al. Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes. Nat Commun. 2020;11(1):2539. doi:10.1038/s41467-019-12438-5
Whiffin N, Karczewski KJ, Zhang X, et al. Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals. Nat Commun. 2020;11(1):2523. doi:10.1038/s41467-019-10717-9