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Publications

Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.

Mejhert N, Kuruvilla L, Gabriel KR, et al. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Mol Cell. 2020. doi:10.1016/j.molcel.2020.01.014

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies.

Martin-Gayo E, Gao C, Chen HR, et al. Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies. Cell Rep. 2020;30(4):984-996.e4. doi:10.1016/j.celrep.2019.12.087

QuantTB - a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data.

Anyansi C, Keo A, Walker BJ, et al. QuantTB - a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data. BMC Genomics. 2020;21(1):80. doi:10.1186/s12864-020-6486-3

Microscaled proteogenomic methods for precision oncology.

Satpathy S, Jaehnig EJ, Krug K, et al. Microscaled proteogenomic methods for precision oncology. Nat Commun. 2020;11(1):532. doi:10.1038/s41467-020-14381-2

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.

Wertz MH, Mitchem MR, Pineda S, et al. Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity. Neuron. 2020. doi:10.1016/j.neuron.2020.01.004

Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits.

Ghoshal A, Uygun DS, Yang L, et al. Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Transl Psychiatry. 2020;10(1):29. doi:10.1038/s41398-020-0685-1

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase.

Catania S, Dumesic PA, Pimentel H, et al. Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase. Cell. 2020;180(2):263-277.e20. doi:10.1016/j.cell.2019.12.012

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators.

Li J, Han S, Li H, et al. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Cell. 2020;180(2):373-386.e15. doi:10.1016/j.cell.2019.12.029

Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

Nusinow DP, Szpyt J, Ghandi M, et al. Quantitative Proteomics of the Cancer Cell Line Encyclopedia. Cell. 2020;180(2):387-402.e16. doi:10.1016/j.cell.2019.12.023

Protein Structure from Experimental Evolution.

Stiffler MA, Poelwijk FJ, Brock KP, et al. Protein Structure from Experimental Evolution. Cell Syst. 2020;10(1):15-24.e5. doi:10.1016/j.cels.2019.11.008