Publications

Transcription Factor Inhibition: Lessons Learned and Emerging Targets.

Chen A, Koehler AN. Transcription Factor Inhibition: Lessons Learned and Emerging Targets. Trends Mol Med. 2020;26(5):508-518. doi:10.1016/j.molmed.2020.01.004

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma.

Tanigawa Y, Wainberg M, Karjalainen J, et al. Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma. PLoS Genet. 2020;16(5):e1008682. doi:10.1371/journal.pgen.1008682

Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes.

Gevaert O, Nabian M, Bakr S, et al. Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes. JCO Clin Cancer Inform. 2020;4:421-435. doi:10.1200/CCI.19.00125

Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer.

Waks AG, Cohen O, Kochupurakkal B, et al. Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer. Ann Oncol. 2020;31(5):590-598. doi:10.1016/j.annonc.2020.02.008

Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population.

Kim J, Yuan C, Babic A, et al. Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2020;29(5):999-1008. doi:10.1158/1055-9965.EPI-19-1389

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles.

Eaton JK, Furst L, Ruberto RA, et al. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. Nat Chem Biol. 2020;16(5):497-506. doi:10.1038/s41589-020-0501-5

Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice.

Donaldson GP, Chou WC, Manson AL, et al. Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice. Nat Microbiol. 2020;5(5):746-756. doi:10.1038/s41564-020-0683-3

Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.

Wang H, Yang J, Schneider JA, De Jager PL, Bennett DA, Zhang HY. Genome-wide interaction analysis of pathological hallmarks in Alzheimer’s disease. Neurobiol Aging. 2020;93:61-68. doi:10.1016/j.neurobiolaging.2020.04.025

The relation of severe malocclusion to patients' mental and behavioral disorders, growth, and speech problems.

Koskela A, Neittaanmäki A, Rönnberg K, Palotie A, Ripatti S, Palotie T. The relation of severe malocclusion to patients’ mental and behavioral disorders, growth, and speech problems. Eur J Orthod. 2020. doi:10.1093/ejo/cjaa028

Massively multiplexed nucleic acid detection using Cas13.

Ackerman CM, Myhrvold C, Thakku SG, et al. Massively multiplexed nucleic acid detection using Cas13. Nature. 2020. doi:10.1038/s41586-020-2279-8

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Publications

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