Publications

Genomic Analysis of Cardiovascular Diseases Utilizing Space Omics and Medical Atlas.

Lee R, Rayhun A, Kim JK, et al. Genomic Analysis of Cardiovascular Diseases Utilizing Space Omics and Medical Atlas. Genes. 2025;16(9). doi:10.3390/genes16090996

PKSmart: an open-source computational model to predict intravenous pharmacokinetics of small molecules.

Seal S, Trapotsi MA, Mahale M, et al. PKSmart: an open-source computational model to predict intravenous pharmacokinetics of small molecules. Journal of cheminformatics. 2025;17(1):147. doi:10.1186/s13321-025-01066-5

In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas.

Jürgensen L, Benfatto S, Schmid S, et al. In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas. Acta neuropathologica. 2025;150(1):34. doi:10.1007/s00401-025-02939-7

Loss of TET2 Facilitates Aggressive Behavior in Cutaneous Melanoma by Inducing PGC1α/Oxidative Phosphorylation (OXPHOS).

Fischer GM, Fang R, Xu S, et al. Loss of TET2 Facilitates Aggressive Behavior in Cutaneous Melanoma by Inducing PGC1α/Oxidative Phosphorylation (OXPHOS). The British journal of dermatology. 2025. doi:10.1093/bjd/ljaf378

From intracellular sensors to systemic resilience: Reframing the biology of stress.

Hartmann J. From intracellular sensors to systemic resilience: Reframing the biology of stress. Neurobiology of stress. 2025;39:100755. doi:10.1016/j.ynstr.2025.100755

Dysregulated smooth muscle cell proliferation and gene expression underlie ACTA2 variant-associated aortopathy.

Pepin ME, Mitchell RN, Gupta RM. Dysregulated smooth muscle cell proliferation and gene expression underlie ACTA2 variant-associated aortopathy. American journal of physiology. Heart and circulatory physiology. 2025. doi:10.1152/ajpheart.00579.2025

In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target.

Fu C, Saddawi-Konefka R, Chinai JM, et al. In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target. Nature communications. 2025;16(1):8572. doi:10.1038/s41467-025-63592-y

Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes.

van der Laan CM, Ip HF, Schipper M, et al. Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. Nature genetics. 2025. doi:10.1038/s41588-025-02383-z

Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women's Health Initiative Memory Study.

Jakubek YA, Smith AP, Leng XI, et al. Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women’s Health Initiative Memory Study. Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2025;21(10):e70737. doi:10.1002/alz.70737

Population-scale Analysis Reveals Germline Loss of SERPING1 (C1-Inhibitor) is a Polyphenotypic Thrombotic Disorder.

Espada AR, Haj A, Jurgens SJ, et al. Population-scale Analysis Reveals Germline Loss of SERPING1 (C1-Inhibitor) is a Polyphenotypic Thrombotic Disorder. Blood advances. 2025. doi:10.1182/bloodadvances.2025017220

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Publications

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