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Publications

Animal models of Chiari malformation types 1 and 2: Mechanistic insights and translational challenges.

Davalan W, Li Q, Hale AT, et al. Animal models of Chiari malformation types 1 and 2: Mechanistic insights and translational challenges. Experimental neurology. 2025;395:115473. doi:10.1016/j.expneurol.2025.115473

Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program.

Sarnowski C, Zhang Y, Ammous F, et al. Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program. Communications biology. 2025;8(1):1352. doi:10.1038/s42003-025-08674-9

A consensus guide to preclinical indirect calorimetry experiments.

Banks AS, Allison DB, Alquier T, et al. A consensus guide to preclinical indirect calorimetry experiments. Nature metabolism. 2025;7(9):1765-1780. doi:10.1038/s42255-025-01360-4

Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α.

Khetarpal SA, Li H, Vitale T, et al. Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α. Nature cardiovascular research. 2025. doi:10.1038/s44161-025-00712-3

Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to spindle dynamics.

Litvak P, Hartley ND, Kast R, et al. Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to spindle dynamics. iScience. 2025;28(9):113393. doi:10.1016/j.isci.2025.113393

Disease-linked regulatory DNA variants and homeostatic transcription factors in epidermis.

Porter DF, Meyers RM, Miao W, et al. Disease-linked regulatory DNA variants and homeostatic transcription factors in epidermis. Nature communications. 2025;16(1):8387. doi:10.1038/s41467-025-63070-5

Graph neural networks learn emergent tissue properties from spatial molecular profiles.

Ali M, Richter S, Ertürk A, Fischer DS, Theis FJ. Graph neural networks learn emergent tissue properties from spatial molecular profiles. Nature communications. 2025;16(1):8419. doi:10.1038/s41467-025-63758-8

Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group.

Colbert SMC, Monson ET, Andreassen OA, et al. Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group. Molecular psychiatry. 2025. doi:10.1038/s41380-025-03271-y

Loss of the tumor suppressor PTEN activates cell-intrinsic interferon signaling to drive immune resistance.

Wang Y, Manokaran C, Chen J, et al. Loss of the tumor suppressor PTEN activates cell-intrinsic interferon signaling to drive immune resistance. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.17.676669

Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling.

Kaul D, Curry AR, Gerstner N, et al. Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2024.06.24.600362