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Publications

Reconstructing the Deep Population History of Central and South America.

Posth C, Nakatsuka N, Lazaridis I, et al. Reconstructing the Deep Population History of Central and South America. Cell. 2018;175(5):1185-1197.e22. doi:10.1016/j.cell.2018.10.027

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.

Cox AG, Tsomides A, Yimlamai D, et al. Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. EMBO J. 2018;37(22). doi:10.15252/embj.2018100294

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Vigneau S, et al. KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell. 2018. doi:10.1016/j.ccell.2018.10.014

Murine Norovirus Infection Induces T1 Inflammatory Responses to Dietary Antigens.

Bouziat R, Biering SB, Kouame E, et al. Murine Norovirus Infection Induces T1 Inflammatory Responses to Dietary Antigens. Cell Host Microbe. 2018;24(5):677-688.e5. doi:10.1016/j.chom.2018.10.004

Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.

Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P. Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability. Cell Death Dis. 2018;9(11):1129. doi:10.1038/s41419-018-1173-x

Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression.

Mowery CT, Reyes JM, Cabal-Hierro L, et al. Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression. Cell Rep. 2018;25(7):1898-1911.e5. doi:10.1016/j.celrep.2018.10.061

Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate.

Bendapudi PK, Robbins A, LeBoeuf N, et al. Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate. Blood Adv. 2018;2(21):2917-2921. doi:10.1182/bloodadvances.2018024430

Distinguishing Variant Pathogenicity From Genetic Diagnosis: How to Know Whether a Variant Causes a Condition.

Biesecker LG, Nussbaum RL, Rehm HL. Distinguishing Variant Pathogenicity From Genetic Diagnosis: How to Know Whether a Variant Causes a Condition. JAMA. 2018;320(18):1929-1930. doi:10.1001/jama.2018.14900

Phagosomal Copper-Promoted Oxidative Attack on Intracellular Mycobacterium tuberculosis.

Libardo DJ, de la Fuente-Núñez C, Anand K, et al. Phagosomal Copper-Promoted Oxidative Attack on Intracellular Mycobacterium tuberculosis. ACS Infect Dis. 2018;4(11):1623-1634. doi:10.1021/acsinfecdis.8b00171

Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression.

Srikanth P, Lagomarsino VN, Pearse RV, et al. Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Transl Psychiatry. 2018;8(1):245. doi:10.1038/s41398-018-0281-9