Jain SU, Williamson KE, Ying AW, et al. A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform. Science (New York, N.Y.). 2026:eaeb3627. doi:10.1126/science.aeb3627
Gene Regulation Observatory
Becerra B, Wittibschlager S, Patel ZM, et al. Nucleotide-resolution mapping of regulatory elements via allelic readout of tiled base editing. Nature communications. 2026. doi:10.1038/s41467-026-69918-8
Tam HT, Peng J, Freeman R, et al. Hyperinnervation inhibits organ-level regeneration in mammalian skin. Cell. 2026. doi:10.1016/j.cell.2026.02.027
Tan J, Le H, Deng J, et al. Characterization of tumour heterogeneity through segmentation-free representation learning on multiplexed imaging data. Nature biomedical engineering. 2025. doi:10.1038/s41551-025-01348-1
Moore MM, Wekhande S, Issner R, et al. Multi-locus CRISPRi targeting with a single truncated guide RNA. Nature communications. 2025;16(1):1357. doi:10.1038/s41467-025-56144-x
Hu Y, Horlbeck MA, Zhang R, et al. Multiscale footprints reveal the organization of cis-regulatory elements. Nature. 2025. doi:10.1038/s41586-024-08443-4
Do C, Jiang G, Cova G, et al. Binding domain mutations provide insight into CTCF’s relationship with chromatin and its contribution to gene regulation. Cell genomics. 2025:100813. doi:10.1016/j.xgen.2025.100813
Weng LC, Rämö JT, Jurgens SJ, et al. The impact of common and rare genetic variants on bradyarrhythmia development. Nature genetics. 2025. doi:10.1038/s41588-024-01978-2
Nagano M, Hansen AS. Distance matters: How protein regulators facilitate enhancer-promoter interactions and transcription. Cell genomics. 2025;5(3):100817. doi:10.1016/j.xgen.2025.100817
Jacques E, Herzog C, Ying K, et al. Invigorating discovery and clinical translation of aging biomarkers. Nature aging. 2025. doi:10.1038/s43587-025-00838-w