ӳ��ý

Proteomics Platform

Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity.

Cutler R, Corveleyn L, Ctortecka C, et al. Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.07.05.602213

IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response.

Simpson MS, De Luca H, Cauthorn S, et al. IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response. The Journal of cell biology. 2024;223(7). doi:10.1083/jcb.202402062

Cell-surface Milieu Remodeling in Human Dendritic Cell Activation.

Udeshi ND, Xu C, Jiang Z, et al. Cell-surface Milieu Remodeling in Human Dendritic Cell Activation. Journal of immunology (Baltimore, Md. : 1950). 2024. doi:10.4049/jimmunol.2400089

A case study to engage students in evolutionary thinking around antibiotic resistance using the MEGA-plate experiment.

Carr SA, Mathews SL, Pruneski JA, Stasulli NM. A case study to engage students in evolutionary thinking around antibiotic resistance using the MEGA-plate experiment. Journal of microbiology & biology education. 2024:e0003924. doi:10.1128/jmbe.00039-24

HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery.

Stražar M, Park J, Abelin JG, et al. HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery. Immunity. 2023. doi:10.1016/j.immuni.2023.05.009

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

Farsi Z, Nicolella A, Simmons SK, et al. Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice. Neuron. 2023. doi:10.1016/j.neuron.2023.08.004

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Xu W, Cheah J, Xu C, et al. Dynamic mapping of proteome trafficking within and between living cells by TransitID. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.07.527548

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.

Hsu YHH, Pintacuda G, Liu R, et al. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience. 2023;26(5):106701. doi:10.1016/j.isci.2023.106701

Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation.

Geffen Y, Anand S, Akiyama Y, et al. Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation. Cell. 2023. doi:10.1016/j.cell.2023.07.013

Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.

Lee SY, Cheah JS, Zhao B, et al. Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.09.531939