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Proteomics Platform

A case study to engage students in evolutionary thinking around antibiotic resistance using the MEGA-plate experiment.

Carr SA, Mathews SL, Pruneski JA, Stasulli NM. A case study to engage students in evolutionary thinking around antibiotic resistance using the MEGA-plate experiment. Journal of microbiology & biology education. 2024:e0003924. doi:10.1128/jmbe.00039-24

Cell-surface Milieu Remodeling in Human Dendritic Cell Activation.

Udeshi ND, Xu C, Jiang Z, et al. Cell-surface Milieu Remodeling in Human Dendritic Cell Activation. Journal of immunology (Baltimore, Md. : 1950). 2024. doi:10.4049/jimmunol.2400089

Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity.

Cutler R, Corveleyn L, Ctortecka C, et al. Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.07.05.602213

Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation.

Cieri N, Hookeri N, Stromhaug K, et al. Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation. Nature biotechnology. 2024. doi:10.1038/s41587-024-02348-3

Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching.

Xu C, Li Z, Lyu C, et al. Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching. Cell. 2024. doi:10.1016/j.cell.2024.06.022

IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response.

Simpson MS, De Luca H, Cauthorn S, et al. IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response. The Journal of cell biology. 2024;223(7). doi:10.1083/jcb.202402062

An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.

Waterbury AL, Kwok HS, Lee C, et al. An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Molecular cell. 2024. doi:10.1016/j.molcel.2024.05.017

Clinical Proteomics: A Promise Becoming Reality.

Gillette MA, Jimenez CR, Carr SA. Clinical Proteomics: A Promise Becoming Reality. Molecular & cellular proteomics : MCP. 2024;23(2):100688. doi:10.1016/j.mcpro.2023.100688

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications.

Ctortecka C, Clark NM, Boyle B, et al. Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.01.20.576369

Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease.

Zhu QM, Hsu YHH, Lassen FH, et al. Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease. Communications biology. 2024;7(1):87. doi:10.1038/s42003-023-05705-1