ӳ��ý

Proteomics Platform

Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity.

Cutler R, Corveleyn L, Ctortecka C, et al. Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.07.05.602213

Cell-surface Milieu Remodeling in Human Dendritic Cell Activation.

Udeshi ND, Xu C, Jiang Z, et al. Cell-surface Milieu Remodeling in Human Dendritic Cell Activation. Journal of immunology (Baltimore, Md. : 1950). 2024. doi:10.4049/jimmunol.2400089

Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway.

Xiao L, Pi X, Goss AC, et al. Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway. Science advances. 2024;10(38):eadp2221. doi:10.1126/sciadv.adp2221

An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.

Waterbury AL, Kwok HS, Lee C, et al. An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Molecular cell. 2024. doi:10.1016/j.molcel.2024.05.017

IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response.

Simpson MS, De Luca H, Cauthorn S, et al. IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response. The Journal of cell biology. 2024;223(7). doi:10.1083/jcb.202402062

Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease.

Zhu QM, Hsu YHH, Lassen FH, et al. Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease. Communications biology. 2024;7(1):87. doi:10.1038/s42003-023-05705-1

High-quality peptide evidence for annotating non-canonical open reading frames as human proteins.

Deutsch EW, Kok LW, Mudge JM, et al. High-quality peptide evidence for annotating non-canonical open reading frames as human proteins. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.09.612016

An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity.

Ctortecka C, Hartlmayr D, Seth A, et al. An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity. Molecular & cellular proteomics : MCP. 2023:100665. doi:10.1016/j.mcpro.2023.100665

Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry.

Phulphagar KM, Ctortecka C, Jacome ASV, et al. Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.10.532106

ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.

Mota I, Patrucco E, Mastini C, et al. ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature cancer. 2023. doi:10.1038/s43018-023-00591-2