Publications

Proteomics Platform

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

Farsi Z, Nicolella A, Simmons SK, et al. Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice. Neuron. 2023. doi:10.1016/j.neuron.2023.08.004

ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.

Mota I, Patrucco E, Mastini C, et al. ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature cancer. 2023. doi:10.1038/s43018-023-00591-2

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset.

Mansur A, Joseph R, Kim E, et al. Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset. eLife. 2023;12. doi:10.7554/eLife.81966

Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production.

Xu J, Kong L, Oliver BA, et al. Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production. Cell reports. 2023;42(7):112708. doi:10.1016/j.celrep.2023.112708

The HLA-II immunopeptidome of SARS-CoV-2.

Weingarten-Gabbay S, Chen DY, Sarkizova S, et al. The HLA-II immunopeptidome of SARS-CoV-2. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.05.26.542482

HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery.

Stražar M, Park J, Abelin JG, et al. HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery. Immunity. 2023. doi:10.1016/j.immuni.2023.05.009

Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model.

Aryal S, Bonanno K, Song B, et al. Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model. Cell reports. 2023;42(5):112497. doi:10.1016/j.celrep.2023.112497

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.

Hsu YHH, Pintacuda G, Liu R, et al. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience. 2023;26(5):106701. doi:10.1016/j.isci.2023.106701

Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases.

Jailkhani N, Clauser KR, Mak HH, et al. Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases. Cancer research. 2023. doi:10.1158/0008-5472.CAN-22-1532

Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Abelin J, Bergstrom E, Rivera K, et al. Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues. Nature communications. 2023;14(1):1851. doi:10.1038/s41467-023-37547-0

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Proteomics Platform

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