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Proteomics Platform

Cell-surface Milieu Remodeling in Human Dendritic Cell Activation.

Udeshi ND, Xu C, Jiang Z, et al. Cell-surface Milieu Remodeling in Human Dendritic Cell Activation. Journal of immunology (Baltimore, Md. : 1950). 2024. doi:10.4049/jimmunol.2400089

Protein phosphatase 1 regulates core PCP signaling.

Song S, Cho B, Weiner AT, et al. Protein phosphatase 1 regulates core PCP signaling. EMBO reports. 2023;24(12):e56997. doi:10.15252/embr.202356997

Integrated Immunopeptidomic and Proteomic Analysis of COVID-19 lung biopsies.

Yin S, Klaeger S, Chea VA, et al. Integrated Immunopeptidomic and Proteomic Analysis of COVID-19 lung biopsies. Frontiers in immunology. 2023;14:1269335. doi:10.3389/fimmu.2023.1269335

HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery.

Stražar M, Park J, Abelin JG, et al. HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery. Immunity. 2023. doi:10.1016/j.immuni.2023.05.009

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.

Hsu YHH, Pintacuda G, Liu R, et al. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience. 2023;26(5):106701. doi:10.1016/j.isci.2023.106701

Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases.

Jailkhani N, Clauser KR, Mak HH, et al. Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases. Cancer research. 2023. doi:10.1158/0008-5472.CAN-22-1532

Chromatin regulator SMARCAL1 modulates cellular lipid metabolism.

Nagai TH, Hartigan C, Mizoguchi T, et al. Chromatin regulator SMARCAL1 modulates cellular lipid metabolism. Communications biology. 2023;6(1):1298. doi:10.1038/s42003-023-05665-6

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Xu W, Cheah J, Xu C, et al. Dynamic mapping of proteome trafficking within and between living cells by TransitID. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.07.527548

An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity.

Ctortecka C, Hartlmayr D, Seth A, et al. An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity. Molecular & cellular proteomics : MCP. 2023:100665. doi:10.1016/j.mcpro.2023.100665

The HLA-II immunopeptidome of SARS-CoV-2.

Weingarten-Gabbay S, Chen DY, Sarkizova S, et al. The HLA-II immunopeptidome of SARS-CoV-2. Cell reports. 2023;43(1):113596. doi:10.1016/j.celrep.2023.113596