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Yeo MJR, Zhang O, Xie X, et al. UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors. Nature. 2025. doi:10.1038/s41586-024-08532-4

Sousa AA, Terrey M, Sakai HA, et al. In vivo prime editing rescues alternating hemiplegia of childhood in mice. Cell. 2025. doi:10.1016/j.cell.2025.06.038

Waterbury AL, Caroli J, Zhang O, et al. Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. Nature communications. 2025;16(1):3156. doi:10.1038/s41467-025-57477-3

Vedagopuram S, Sindi S, Chaudhary S, et al. Ultrasmall chemogenetic tags with group-transfer ligands. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.10.653252

Pergu R, Vedagopuram S, Kokkonda P, et al. Phosphorylation-inducing molecules for regulating dynamic cellular processes. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.10.652895

Xie X, Zhang O, Yeo MJR, et al. Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations. Nature. 2025. doi:10.1038/s41586-024-08533-3

Zhang J, Ali MY, Chong HB, et al. Oxidation of retromer complex controls mitochondrial translation. Nature. 2025. doi:10.1038/s41586-025-08756-y

Wu B, Chang H, Singh P, et al. Small molecule modulators of TOX protein re-invigorate T cell activity. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.03.03.641115

Musunuru K, Grandinette S, Wang X, et al. Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease. The New England journal of medicine. 2025. doi:10.1056/NEJMoa2504747

Khirallah J, Bloomer H, Wich D, et al. In vivo base editing of Angptl3 via lipid nanoparticles to treat cardiovascular disease. Molecular therapy. Nucleic acids. 2025;36(2):102486. doi:10.1016/j.omtn.2025.102486