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Publications

Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. The Lancet. Infectious diseases. 2025. doi:10.1016/S1473-3099(25)00689-9

Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy.

Chen Z, Zhu Z, Hu T, Yao C, Wu T. Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy. Cellular & molecular immunology. 2025. doi:10.1038/s41423-025-01378-4

Lipoprotein(a) and Outcomes in Worsening Heart Failure With Preserved Ejection Fraction: The PARAGLIDE-HF Trial.

Paruchuri K, Mentz RJ, Tsimikas S, et al. Lipoprotein(a) and Outcomes in Worsening Heart Failure With Preserved Ejection Fraction: The PARAGLIDE-HF Trial. JACC. Heart failure. 2025:102843. doi:10.1016/j.jchf.2025.102843

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias.

Fleming TJ, Antoszewski M, Lambo S, et al. CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias. Blood. 2025;146(25):3019-3035. doi:10.1182/blood.2025028954

MTHFR allele and one-carbon metabolic profile predict severity of COVID-19.

Petrova B, Syphurs C, Culhane AJ, et al. MTHFR allele and one-carbon metabolic profile predict severity of COVID-19. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(51):e2509118122. doi:10.1073/pnas.2509118122

A functional map of CDK-drug interactions at single amino acid resolution.

Gould SI, Acosta J, Bielo LB, et al. A functional map of CDK-drug interactions at single amino acid resolution. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.11.02.685764

PMCID

PMC12637707

Genome-wide analysis in over 1.6 million participants uncovers 147 loci associated with obstructive sleep apnoea.

García-Marín LM, Ceja Z, Parasuraman A, et al. Genome-wide analysis in over 1.6 million participants uncovers 147 loci associated with obstructive sleep apnoea. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.11.08.25339824

PMCID

PMC12642705

Simulation and empirical evaluation of biologically-informed neural network performance.

Miller GA, Roman A, Glettig M, et al. Simulation and empirical evaluation of biologically-informed neural network performance. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.11.13.687845

PMCID

PMC12642320

Higher promoter methylation of the Ubiquitin Associated and SH3 domain containing A (UBASH3A) gene is associated with T-lymphocyte ontogeny and reduced susceptibility to early-onset sepsis.

Wang Z, Amenyogbe N, Ben-Othman R, et al. Higher promoter methylation of the Ubiquitin Associated and SH3 domain containing A (UBASH3A) gene is associated with T-lymphocyte ontogeny and reduced susceptibility to early-onset sepsis. The Journal of infectious diseases. 2025. doi:10.1093/infdis/jiaf636

Contrastive learning enhances fairness in pathology artificial intelligence systems.

Lin SY, Tsai PC, Su FY, et al. Contrastive learning enhances fairness in pathology artificial intelligence systems. Cell reports. Medicine. 2025;6(12):102527. doi:10.1016/j.xcrm.2025.102527