Publications

Adrenergic signaling coordinates distant and local responses to amputation in axolotl.

Payzin-Dogru D, Froitzheim T, Blair SJ, et al. Adrenergic signaling coordinates distant and local responses to amputation in axolotl. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2021.12.29.474455

Deep-learning triage of 3D pathology datasets for comprehensive and efficient pathologist assessments.

Gao G, Yan R, Song AH, et al. Deep-learning triage of 3D pathology datasets for comprehensive and efficient pathologist assessments. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.07.20.665804

Endogenous gene editing of alveolar organoids reveals that expression of pathogenic variant SFTPC-I73T disrupts endosomal function, epithelial polarity and wound healing.

Rutherford EN, Sun D, Lim K, et al. Endogenous gene editing of alveolar organoids reveals that expression of pathogenic variant SFTPC-I73T disrupts endosomal function, epithelial polarity and wound healing. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.07.22.665497

Segmental copy number amplifications are stable in the absence of selection.

De T, Ben Nun N, Spealman P, et al. Segmental copy number amplifications are stable in the absence of selection. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.07.21.665951

TGF-β Coordinates Alanine Synthesis and Import for Myofibroblast Differentiation in Pulmonary Fibrosis.

Li F, Vigder N, Ziehr DR, et al. TGF-β Coordinates Alanine Synthesis and Import for Myofibroblast Differentiation in Pulmonary Fibrosis. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.07.23.666333

Real-time, multi-pathogen wastewater genomic surveillance with Freyja 2.

Levy JI, Gangavarapu P, Pilz DA, et al. Real-time, multi-pathogen wastewater genomic surveillance with Freyja 2. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.07.26.25332245

Implementing a context-augmented large language model to guide precision cancer medicine.

Jun H, Tanaka Y, Johri S, et al. Implementing a context-augmented large language model to guide precision cancer medicine. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.05.09.25327312

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

Huerta-Chagoya A, Kim J, Mandla R, et al. Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.07.21.25331778

Improved Bicyclic Pyrrolidine Analogues Inhibit Growth In Vitro and Cure Infection In Vivo.

Uddin T, Xie H, Mittal P, et al. Improved Bicyclic Pyrrolidine Analogues Inhibit Growth In Vitro and Cure Infection In Vivo. Journal of medicinal chemistry. 2025;68(16):17350-17363. doi:10.1021/acs.jmedchem.5c00865

Host-intrinsic and host-extrinsic factors modulate immunity to Mtb infection, reinfection, and noncanonical vaccination routes.

Bromley JD, Simonson AW, Shalek AK, Flynn JL. Host-intrinsic and host-extrinsic factors modulate immunity to Mtb infection, reinfection, and noncanonical vaccination routes. Cell reports. Medicine. 2025;6(8):102286. doi:10.1016/j.xcrm.2025.102286

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Publications

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