Publications

Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk.

Kany S, Rämö JT, Hou C, et al. Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk. Nature genetics. 2025. doi:10.1038/s41588-025-02397-7

Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.

Small AM, Yang TY, Itoh S, et al. Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. Nature genetics. 2025. doi:10.1038/s41588-025-02417-6

Simulated patient systems powered by large language model-based AI agents offer potential for transforming medical education.

Yu H, Zhou J, Li L, et al. Simulated patient systems powered by large language model-based AI agents offer potential for transforming medical education. Communications medicine. 2025. doi:10.1038/s43856-025-01283-x

Germline predisposition to oncogenic alkylating damage in colorectal cancer.

Gurjao C, Cazaubiel J, Tan C, et al. Germline predisposition to oncogenic alkylating damage in colorectal cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2025. doi:10.1158/1055-9965.EPI-25-1006

Implementing a trauma-informed approach in a tiered model of pediatric population mental health care: a pilot study in primary and secondary care.

Mikesell C, Blevins EJ, Eschtruth M, et al. Implementing a trauma-informed approach in a tiered model of pediatric population mental health care: a pilot study in primary and secondary care. BMC health services research. 2025;25(1):1603. doi:10.1186/s12913-025-13356-7

Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes.

Harrison TA, Zaidi SH, Yin H, et al. Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes. BMC cancer. 2025. doi:10.1186/s12885-025-15440-x

Integrating synthetic biology to understand and engineer the heart, lung, blood, and sleep systems.

Chaikof EL, Chen J, Gillette MU, et al. Integrating synthetic biology to understand and engineer the heart, lung, blood, and sleep systems. Cell systems. 2025;16(12):101446. doi:10.1016/j.cels.2025.101446

Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. The Lancet. Infectious diseases. 2025. doi:10.1016/S1473-3099(25)00689-9

Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy.

Chen Z, Zhu Z, Hu T, Yao C, Wu T. Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy. Cellular & molecular immunology. 2025. doi:10.1038/s41423-025-01378-4

Lipoprotein(a) and Outcomes in Worsening Heart Failure With Preserved Ejection Fraction: The PARAGLIDE-HF Trial.

Paruchuri K, Mentz RJ, Tsimikas S, et al. Lipoprotein(a) and Outcomes in Worsening Heart Failure With Preserved Ejection Fraction: The PARAGLIDE-HF Trial. JACC. Heart failure. 2025:102843. doi:10.1016/j.jchf.2025.102843

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Publications

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