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Publications

Bidirectional cross talk between patient-derived melanoma and cancer-associated fibroblasts promotes invasion and proliferation.

Izar B, Joyce CE, Goff S, et al. Bidirectional cross talk between patient-derived melanoma and cancer-associated fibroblasts promotes invasion and proliferation. Pigment Cell Melanoma Res. 2016;29(6):656-668. doi:10.1111/pcmr.12513

Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations.

Wu S, Tan J, Yang Y, et al. Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations. Hum Genet. 2016;135(11):1279-1286. doi:10.1007/s00439-016-1718-y

ESR1-Amplification-Associated Estrogen Receptor α Activity in Breast Cancer.

Holst F, Singer CF. ESR1-Amplification-Associated Estrogen Receptor α Activity in Breast Cancer. Trends Endocrinol Metab. 2016;27(11):751-752. doi:10.1016/j.tem.2016.08.002

Polycomb and trithorax opposition in development and disease.

Poynter ST, Kadoch C. Polycomb and trithorax opposition in development and disease. Wiley Interdiscip Rev Dev Biol. 2016;5(6):659-688. doi:10.1002/wdev.244

Genomic Analysis of the Evolution of Fluoroquinolone Resistance in Mycobacterium tuberculosis Prior to Tuberculosis Diagnosis.

Zhang D, Gomez JE, Chien JY, et al. Genomic Analysis of the Evolution of Fluoroquinolone Resistance in Mycobacterium tuberculosis Prior to Tuberculosis Diagnosis. Antimicrob Agents Chemother. 2016;60(11):6600-6608. doi:10.1128/AAC.00664-16

Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms.

Jaffe JD, Feeney CM, Patel J, Lu X, Mani DR. Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms. J Am Soc Mass Spectrom. 2016;27(11):1745-1751. doi:10.1007/s13361-016-1465-2

Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor.

Garvie CW, Fraley CV, Elowe NH, et al. Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor. Protein Sci. 2016;25(11):2018-2027. doi:10.1002/pro.3019

Quantifying unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects.

Zou J, Valiant G, Valiant P, et al. Quantifying unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects. Nat Commun. 2016;7:13293. doi:10.1038/ncomms13293

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation.

Villar RF, Patel J, Weaver GC, et al. Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation. Sci Rep. 2016;6:36298. doi:10.1038/srep36298

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease.

O’Brien VP, Hannan TJ, Yu L, et al. A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease. Nat Microbiol. 2016;2:16196. doi:10.1038/nmicrobiol.2016.196