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Publications

Immune Cell Intolerance for Excess Cholesterol.

Widenmaier SB, Hotamışlıgil GS. Immune Cell Intolerance for Excess Cholesterol. Immunity. 2016;45(6):1186-1188. doi:10.1016/j.immuni.2016.12.006

Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives.

Nelson SD, Wawer MJ, Schreiber SL. Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives. Org Lett. 2016;18(24):6280-6283. doi:10.1021/acs.orglett.6b03118

Old dog, new tricks: IL-6 cluster signaling promotes pathogenic TH17 cell differentiation.

Quintana FJ. Old dog, new tricks: IL-6 cluster signaling promotes pathogenic TH17 cell differentiation. Nat Immunol. 2016;18(1):8-10. doi:10.1038/ni.3637

Accurate Estimation of Fungal Diversity and Abundance through Improved Lineage-Specific Primers Optimized for Illumina Amplicon Sequencing.

Taylor L, Walters WA, Lennon NJ, et al. Accurate Estimation of Fungal Diversity and Abundance through Improved Lineage-Specific Primers Optimized for Illumina Amplicon Sequencing. Appl Environ Microbiol. 2016;82(24):7217-7226. doi:10.1128/AEM.02576-16

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.

Muranen T, Selfors LM, Hwang J, et al. ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP. Cancer Res. 2016;76(24):7168-7180. doi:10.1158/0008-5472.CAN-16-0155

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.

Khera AV, Emdin CA, Drake I, et al. Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. N Engl J Med. 2016;375(24):2349-2358. doi:10.1056/NEJMoa1605086

Relationship between handedness and joint involvement in rheumatoid arthritis.

Yaku A, Hashimoto M, Furu M, et al. Relationship between handedness and joint involvement in rheumatoid arthritis. Sci Rep. 2016;6:39180. doi:10.1038/srep39180

Omalizumab Is Associated with Reduced Acute Severity of Rhinovirus-triggered Asthma Exacerbation.

Kantor DB, McDonald MC, Stenquist N, et al. Omalizumab Is Associated with Reduced Acute Severity of Rhinovirus-triggered Asthma Exacerbation. Am J Respir Crit Care Med. 2016;194(12):1552-1555. doi:10.1164/rccm.201606-1145LE

An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.

Wu L, Zhou B, Oshiro-Rapley N, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167(7):1705-1718.e13. doi:10.1016/j.cell.2016.11.055

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens.

Dixit A, Parnas O, Li B, et al. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016;167(7):1853-1866.e17. doi:10.1016/j.cell.2016.11.038