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Publications

Genomic Analysis of the Evolution of Fluoroquinolone Resistance in Mycobacterium tuberculosis Prior to Tuberculosis Diagnosis.

Zhang D, Gomez JE, Chien JY, et al. Genomic Analysis of the Evolution of Fluoroquinolone Resistance in Mycobacterium tuberculosis Prior to Tuberculosis Diagnosis. Antimicrob Agents Chemother. 2016;60(11):6600-6608. doi:10.1128/AAC.00664-16

Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms.

Jaffe JD, Feeney CM, Patel J, Lu X, Mani DR. Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms. J Am Soc Mass Spectrom. 2016;27(11):1745-1751. doi:10.1007/s13361-016-1465-2

Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor.

Garvie CW, Fraley CV, Elowe NH, et al. Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor. Protein Sci. 2016;25(11):2018-2027. doi:10.1002/pro.3019

Quantifying unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects.

Zou J, Valiant G, Valiant P, et al. Quantifying unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects. Nat Commun. 2016;7:13293. doi:10.1038/ncomms13293

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation.

Villar RF, Patel J, Weaver GC, et al. Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation. Sci Rep. 2016;6:36298. doi:10.1038/srep36298

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease.

O’Brien VP, Hannan TJ, Yu L, et al. A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease. Nat Microbiol. 2016;2:16196. doi:10.1038/nmicrobiol.2016.196

Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging.

Tian F, Yang W, Mordes DA, et al. Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging. Nat Commun. 2016;7:13283. doi:10.1038/ncomms13283

Histone acetylation of glucose-induced thioredoxin-interacting protein gene expression in pancreatic islets.

Bompada P, Atac D, Luan C, et al. Histone acetylation of glucose-induced thioredoxin-interacting protein gene expression in pancreatic islets. Int J Biochem Cell Biol. 2016. doi:10.1016/j.biocel.2016.10.022

Genetic Risk Prediction of Atrial Fibrillation.

Lubitz SA, Yin X, Lin H, et al. Genetic Risk Prediction of Atrial Fibrillation. Circulation. 2016. doi:10.1161/CIRCULATIONAHA.116.024143

The role of rare protein-coding variants to anti-TNF treatment response in rheumatoid arthritis.

Cui J, Diogo D, Stahl EA, et al. The role of rare protein-coding variants to anti-TNF treatment response in rheumatoid arthritis. Arthritis Rheumatol. 2016. doi:10.1002/art.39966