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Publications

CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development.

Ray MK, Wiskow O, King MJ, et al. CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development. J Biol Chem. 2016;291(37):19558-72. doi:10.1074/jbc.M116.730853

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.

Mayers JR, Torrence ME, Danai LV, et al. Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers. Science. 2016;353(6304):1161-5. doi:10.1126/science.aaf5171

MicroRNA inhibition fine-tunes and provides robustness to the restriction point switch of the cell cycle.

Del Rosario RCH, Damasco JRC, Aguda BD. MicroRNA inhibition fine-tunes and provides robustness to the restriction point switch of the cell cycle. Sci Rep. 2016;6:32823. doi:10.1038/srep32823

Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β.

Wang Y, Wach JY, Sheehan P, et al. Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β. ACS Med Chem Lett. 2016;7(9):852-6. doi:10.1021/acsmedchemlett.6b00230

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.

Singer M, Wang C, Cong L, et al. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 2016;166(6):1500-1511.e9. doi:10.1016/j.cell.2016.08.052

The impact of personal genomics on risk perceptions and medical decision-making.

Krieger JL, Murray F, Roberts S, Green RC. The impact of personal genomics on risk perceptions and medical decision-making. Nat Biotechnol. 2016;34(9):912-8. doi:10.1038/nbt.3661

Gut Microbiota, Inflammation, and Colorectal Cancer.

Brennan CA, Garrett WS. Gut Microbiota, Inflammation, and Colorectal Cancer. Annu Rev Microbiol. 2016;70:395-411. doi:10.1146/annurev-micro-102215-095513

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

Sidik SM, Huet D, Ganesan SM, et al. A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Cell. 2016;166(6):1423-1435.e12. doi:10.1016/j.cell.2016.08.019

Genome-wide association study of antisocial personality disorder.

Rautiainen MR, Paunio T, Repo-Tiihonen E, et al. Genome-wide association study of antisocial personality disorder. Transl Psychiatry. 2016;6(9):e883. doi:10.1038/tp.2016.155

In vivo Ebola virus infection leads to a strong innate response in circulating immune cells.

Caballero IS, Honko AN, Gire SK, et al. In vivo Ebola virus infection leads to a strong innate response in circulating immune cells. BMC Genomics. 2016;17:707. doi:10.1186/s12864-016-3060-0