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Publications

G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.

Kedersha N, Panas MD, Achorn CA, et al. G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol. 2016;212(7):845-60. doi:10.1083/jcb.201508028

Personal Genome Sequencing in Ostensibly Healthy Individuals and the PeopleSeq Consortium.

Linderman MD, Nielsen DE, Green RC. Personal Genome Sequencing in Ostensibly Healthy Individuals and the PeopleSeq Consortium. J Pers Med. 2016;6(2). doi:10.3390/jpm6020014

CANCER. The oncogene makes its escape.

Wala J, Beroukhim R. CANCER. The oncogene makes its escape. Science. 2016;351(6280):1398-9. doi:10.1126/science.aaf5542

Survey of variation in human transcription factors reveals prevalent DNA binding changes.

Barrera LA, Vedenko A, Kurland JV, et al. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science. 2016;351(6280):1450-4. doi:10.1126/science.aad2257

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.

McGranahan N, Furness AJS, Rosenthal R, et al. Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade. Science. 2016;351(6280):1463-9. doi:10.1126/science.aaf1490

Function and evolution of local repeats in the Firre locus.

Hacisuleyman E, Shukla CJ, Weiner CL, Rinn JL. Function and evolution of local repeats in the Firre locus. Nat Commun. 2016;7:11021. doi:10.1038/ncomms11021

PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.

Tran MT, Zsengeller ZK, Berg AH, et al. PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 2016;531(7595):528-32. doi:10.1038/nature17184

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.

Chantranupong L, Scaria SM, Saxton RA, et al. The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway. Cell. 2016;165(1):153-64. doi:10.1016/j.cell.2016.02.035

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Stitziel NO, Stirrups KE, et al. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med. 2016;374(12):1134-44. doi:10.1056/NEJMoa1507652

System-wide Analysis of the T Cell Response.

Covacu R, Philip H, Jaronen M, et al. System-wide Analysis of the T Cell Response. Cell Rep. 2016;14(11):2733-44. doi:10.1016/j.celrep.2016.02.056