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Publications

Reducing Cardiovascular Risk Using Genomic Information in the Era of Precision Medicine.

Natarajan P, O’Donnell CJ. Reducing Cardiovascular Risk Using Genomic Information in the Era of Precision Medicine. Circulation. 2016;133(12):1155-9. doi:10.1161/CIRCULATIONAHA.116.021765

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation.

Kim N, Cho A, Watanabe H, et al. Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation. Oncotarget. 2016;7(12):13797-809. doi:10.18632/oncotarget.7318

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.

Strickland KC, Howitt BE, Shukla SA, et al. Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer. Oncotarget. 2016;7(12):13587-98. doi:10.18632/oncotarget.7277

Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures.

Lu Y, Zhong C, Wang L, et al. Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures. Nat Commun. 2016;7:10962. doi:10.1038/ncomms10962

Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients.

Ruan Y, Jiang J, Guo L, et al. Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients. Sci Rep. 2016;6:23368. doi:10.1038/srep23368

Molecular sled sequences are common in mammalian proteins.

Xiong K, Blainey PC. Molecular sled sequences are common in mammalian proteins. Nucleic Acids Res. 2016;44(5):2266-73. doi:10.1093/nar/gkw035

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.

Howitt MR, Lavoie S, Michaud M, et al. Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science. 2016;351(6279):1329-33. doi:10.1126/science.aaf1648

Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer.

Du Z, Sun T, Hacisuleyman E, et al. Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer. Nat Commun. 2016;7:10982. doi:10.1038/ncomms10982

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.

Chen F, Zhang Y, Senbabaoglu Y, et al. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Rep. 2016;14(10):2476-89. doi:10.1016/j.celrep.2016.02.024

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes.

Pers TH, Timshel P, Ripke S, et al. Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes. Hum Mol Genet. 2016;25(6):1247-54. doi:10.1093/hmg/ddw007