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Publications

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.

Gusev A, Shi H, Kichaev G, et al. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016;7:10979. doi:10.1038/ncomms10979

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.

Chouchani ET, Kazak L, Jedrychowski MP, et al. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. 2016;532(7597):112-6. doi:10.1038/nature17399

Thalamic reticular impairment underlies attention deficit in Ptchd1(Y/-) mice.

Wells MF, Wimmer RD, Schmitt I, Feng G, Halassa MM. Thalamic reticular impairment underlies attention deficit in Ptchd1(Y/-) mice. Nature. 2016;532(7597):58-63. doi:10.1038/nature17427

Improved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides.

Ma J, Diedrich JK, Jungreis I, et al. Improved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides. Anal Chem. 2016;88(7):3967-75. doi:10.1021/acs.analchem.6b00191

Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later.

Spartano NL, Himali JJ, Beiser AS, et al. Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later. Neurology. 2016;86(14):1313-9. doi:10.1212/WNL.0000000000002415

Parsing psychosis subtypes through investigations of rare genetic variants.

Bergen SE. Parsing psychosis subtypes through investigations of rare genetic variants. EBioMedicine. 2016;6:16-7. doi:10.1016/j.ebiom.2016.04.009

Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood.

Lewis-Smith D, Kamer KJ, Griffin H, et al. Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood. Neurol Genet. 2016;2(2):e59. doi:10.1212/NXG.0000000000000059

Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.

Börnigen D, Tyekucheva S, Wang X, et al. Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer. PLoS Comput Biol. 2016;12(4):e1004820. doi:10.1371/journal.pcbi.1004820

Ancient mitochondrial DNA provides high-resolution time scale of the peopling of the Americas.

Llamas B, Fehren-Schmitz L, Valverde G, et al. Ancient mitochondrial DNA provides high-resolution time scale of the peopling of the Americas. Sci Adv. 2016;2(4):e1501385. doi:10.1126/sciadv.1501385

Lifting Up the HAT: Synthetic Lethal Screening Reveals a Novel Vulnerability at the CBP-p300 Axis.

Kadoch C. Lifting Up the HAT: Synthetic Lethal Screening Reveals a Novel Vulnerability at the CBP-p300 Axis. Cancer Discov. 2016;6(4):350-2. doi:10.1158/2159-8290.CD-16-0163