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Publications

Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs.

Chen J, Shishkin AA, Zhu X, et al. Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs. Genome Biol. 2016;17:19. doi:10.1186/s13059-016-0880-9

Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA.

Mangel WF, McGrath WJ, Xiong K, Graziano V, Blainey PC. Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA. Nat Commun. 2016;7:10202. doi:10.1038/ncomms10202

Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.

Benoit JB, Adelman ZN, Reinhardt K, et al. Unique features of a global human ectoparasite identified through sequencing of the bed bug genome. Nat Commun. 2016;7:10165. doi:10.1038/ncomms10165

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis.

Dubin K, Callahan MK, Ren B, et al. Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis. Nat Commun. 2016;7:10391. doi:10.1038/ncomms10391

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.

Keenan T, Zhao W, Rasheed A, et al. Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study. J Am Coll Cardiol. 2016;67(4):407-16. doi:10.1016/j.jacc.2015.10.086

Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction.

Santhanakrishnan R, Wang N, Larson MG, et al. Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction. Circulation. 2016;133(5):484-92. doi:10.1161/CIRCULATIONAHA.115.018614

Dysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsy.

Muona M, Fukata Y, Anttonen AK, et al. Dysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsy. Neurol Genet. 2016;2(1):e46. doi:10.1212/NXG.0000000000000046

Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity.

Caron A, Labbé SM, Lanfray D, et al. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity. Mol Metab. 2016;5(2):102-12. doi:10.1016/j.molmet.2015.11.005

Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy.

Gannon HS, Kaplan N, Tsherniak A, et al. Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy. Mol Cancer Res. 2016;14(2):207-15. doi:10.1158/1541-7786.MCR-15-0321

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Kilpeläinen TO, Carli JFM, Skowronski AA, et al. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun. 2016;7:10494. doi:10.1038/ncomms10494