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Publications

A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation.

Fields AP, Rodriguez EH, Jovanovic M, et al. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Mol Cell. 2015;60(5):816-27. doi:10.1016/j.molcel.2015.11.013

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity.

Wang C, Yosef N, Gaublomme J, et al. CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell. 2015;163(6):1413-27. doi:10.1016/j.cell.2015.10.068

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity.

Gaublomme JT, Yosef N, Lee Y, et al. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. Cell. 2015;163(6):1400-12. doi:10.1016/j.cell.2015.11.009

Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.

Palamara PF, Francioli LC, Wilton PR, et al. Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates. Am J Hum Genet. 2015;97(6):775-89. doi:10.1016/j.ajhg.2015.10.006

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

D’Gama AM, Pochareddy S, Li M, et al. Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms. Neuron. 2015;88(5):910-7. doi:10.1016/j.neuron.2015.11.009

A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.

Petrovics G, Li H, Stümpel T, et al. A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men. EBioMedicine. 2015;2(12):1957-64. doi:10.1016/j.ebiom.2015.10.028

Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.

Lu H, Clauser KR, Tam WL, et al. Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol. 2015;17(12):1607. doi:10.1038/ncb3281

High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED.

Kaminski J, Gibson MK, Franzosa EA, Segata N, Dantas G, Huttenhower C. High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED. PLoS Comput Biol. 2015;11(12):e1004557. doi:10.1371/journal.pcbi.1004557

A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed.

Palchaudhuri R, Lambrecht MJ, Botham RC, et al. A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed. Cell Rep. 2015;13(9):2027-36. doi:10.1016/j.celrep.2015.10.042

Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection.

Mesquita RD, Vionette-Amaral RJ, Lowenberger C, et al. Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection. Proc Natl Acad Sci U S A. 2015;112(48):14936-41. doi:10.1073/pnas.1506226112