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Publications

Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors.

Burr R, Leshchiner I, Costantino CL, et al. Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors. Nature cancer. 2024. doi:10.1038/s43018-024-00840-y

Discovery of BAY 2666605, a Molecular Glue for PDE3A and SLFN12.

Lewis TA, Ellermann M, Kopitz C, et al. Discovery of BAY 2666605, a Molecular Glue for PDE3A and SLFN12. ACS medicinal chemistry letters. 2024;15(10):1662-1667. doi:10.1021/acsmedchemlett.4c00336

UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract.

Stritt K, Roth B, Masnada A, et al. UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract. Trials. 2024;25(1):682. doi:10.1186/s13063-024-08526-7

"Monitoring inflammatory, immune system mediators, and mitochondrial changes related to brain metabolism during space flight".

Tocci D, Ducai T, Stoute CAB, et al. "Monitoring inflammatory, immune system mediators, and mitochondrial changes related to brain metabolism during space flight". Frontiers in immunology. 2024;15:1422864. doi:10.3389/fimmu.2024.1422864

Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia.

Schneider C, Spaink H, Alexe G, et al. Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia. Cancer research. 2024;84(20):3354-3370. doi:10.1158/0008-5472.CAN-23-3560

Second Primary Malignancies after CAR T-Cell Therapy: A Systematic Review and Meta-analysis of 5,517 Lymphoma and Myeloma Patients.

Tix T, Alhomoud M, Shouval R, et al. Second Primary Malignancies after CAR T-Cell Therapy: A Systematic Review and Meta-analysis of 5,517 Lymphoma and Myeloma Patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024;30(20):4690-4700. doi:10.1158/1078-0432.CCR-24-1798

Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics.

Baek K, Metivier RJ, Burman SSR, et al. Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.11.612438

Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution.

Baya NA, Erdem IS, Venkatesh SS, et al. Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.09.19.24313913

Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS.

Xu J, Zhu K, Cai J, et al. Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.19.613975

Mosaic loss of chromosome Y, tobacco smoking, and risk of age-related lung diseases: insights from two prospective cohorts.

Weng C, Zhao Y, Song M, et al. Mosaic loss of chromosome Y, tobacco smoking, and risk of age-related lung diseases: insights from two prospective cohorts. The European respiratory journal. 2024. doi:10.1183/13993003.00968-2024