Publications

A latent Axin2/Scx progenitor pool is the central organizer of tendon healing.

Grinstein M, Tsai SL, Montoro D, et al. A latent Axin2/Scx progenitor pool is the central organizer of tendon healing. NPJ Regenerative medicine. 2024;9(1):30. doi:10.1038/s41536-024-00370-2

Alternate RNA decoding results in stable and abundant proteins in mammals.

Tsour S, Machne R, Leduc A, et al. Alternate RNA decoding results in stable and abundant proteins in mammals. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.08.26.609665

Fine-mapping a genome-wide meta-analysis of 98,374 migraine cases identifies 181 sets of candidate causal variants.

Hautakangas H, Palotie A, Pirinen M, , , . Fine-mapping a genome-wide meta-analysis of 98,374 migraine cases identifies 181 sets of candidate causal variants. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.05.20.24307608

Programmed ribosomal frameshifting during mRNA decoding generates a constitutively active mediator of kinesin-1-dependent lysosome transport.

Khan YA, De Pace R, Jungreis I, et al. Programmed ribosomal frameshifting during mRNA decoding generates a constitutively active mediator of kinesin-1-dependent lysosome transport. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.08.30.610563

Complex genetic variation in nearly complete human genomes.

Logsdon GA, Ebert P, Audano PA, et al. Complex genetic variation in nearly complete human genomes. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.24.614721

Discovery of electrophilic degraders that exploit SAr chemistry.

Zhuang Z, Byun WS, Kozicka Z, et al. Discovery of electrophilic degraders that exploit SAr chemistry. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.25.615094

Per- and poly-fluoroalkyl substances (PFAS) accelerate biological aging mediated by increased C-reactive protein.

Zhao Z, Zhou J, Shi A, et al. Per- and poly-fluoroalkyl substances (PFAS) accelerate biological aging mediated by increased C-reactive protein. Journal of hazardous materials. 2024;480:136090. doi:10.1016/j.jhazmat.2024.136090

Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors.

Burr R, Leshchiner I, Costantino CL, et al. Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors. Nature cancer. 2024. doi:10.1038/s43018-024-00840-y

Per- and poly-fluoroalkyl substances (PFAS) accelerate biological aging mediated by increased C-reactive protein.

Zhao Z, Zhou J, Shi A, et al. Per- and poly-fluoroalkyl substances (PFAS) accelerate biological aging mediated by increased C-reactive protein. Journal of hazardous materials. 2024;480:136090. doi:10.1016/j.jhazmat.2024.136090

UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract.

Stritt K, Roth B, Masnada A, et al. UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract. Trials. 2024;25(1):682. doi:10.1186/s13063-024-08526-7