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Publications

Physical Activity and Cardiovascular Outcomes in Phenotype-Negative Cardiomyopathy Variant Carriers.

Ajufo E, Kany S, Jurgens SJ, et al. Physical Activity and Cardiovascular Outcomes in Phenotype-Negative Cardiomyopathy Variant Carriers. JAMA cardiology. 2025. doi:10.1001/jamacardio.2025.4466

New methodological approaches and insights gained toward understanding the evolved human skeleton.

Senevirathne G, Capellini TD. New methodological approaches and insights gained toward understanding the evolved human skeleton. Current opinion in genetics & development. 2025;95:102413. doi:10.1016/j.gde.2025.102413

Germline Variants as Risk Factors for Early-Onset Lung Adenocarcinoma.

Yermalovich A, Meyerson M. Germline Variants as Risk Factors for Early-Onset Lung Adenocarcinoma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2025;20(11):1573-1576. doi:10.1016/j.jtho.2025.08.012

nELISA: a high-throughput, high-plex platform enables quantitative profiling of the inflammatory secretome.

Dagher M, Ongo G, Robichaud N, et al. nELISA: a high-throughput, high-plex platform enables quantitative profiling of the inflammatory secretome. Nature methods. 2025. doi:10.1038/s41592-025-02861-6

Monod: model-based discovery and integration through fitting stochastic transcriptional dynamics to single-cell sequencing data.

Gorin G, Chari T, Carilli M, Vastola JJ, Pachter L. Monod: model-based discovery and integration through fitting stochastic transcriptional dynamics to single-cell sequencing data. Nature methods. 2025. doi:10.1038/s41592-025-02832-x

Degradable cyclic amino alcohol ionizable lipids as vectors for potent influenza mRNA vaccines.

Rudra A, Gupta A, Reed K, et al. Degradable cyclic amino alcohol ionizable lipids as vectors for potent influenza mRNA vaccines. Nature nanotechnology. 2025. doi:10.1038/s41565-025-02044-6

MYC amplification and MYC protein expression are poor prognostic markers in pediatric and young adult osteosarcoma.

Nagy MR, Puopolo O, Alston E, et al. MYC amplification and MYC protein expression are poor prognostic markers in pediatric and young adult osteosarcoma. Cancer. 2025;131(22):e70161. doi:10.1002/cncr.70161

Global, regional and national burden of epilepsy in children and adolescents, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021.

Kim YS, Kim MS, Park S, et al. Global, regional and national burden of epilepsy in children and adolescents, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. European journal of clinical investigation. 2025:e70139. doi:10.1111/eci.70139

Accelerated biological aging and its hallmarks in DNA methylation drive the association between unhealthy lifestyles and the onset of colorectal cancer.

Sun J, Liu M, Zhang X, et al. Accelerated biological aging and its hallmarks in DNA methylation drive the association between unhealthy lifestyles and the onset of colorectal cancer. EBioMedicine. 2025;122:106005. doi:10.1016/j.ebiom.2025.106005

scCausalVI disentangles single-cell perturbation responses with causality-aware generative model.

An S, Cho JW, Cao K, Xiong J, Hemberg M, Wan L. scCausalVI disentangles single-cell perturbation responses with causality-aware generative model. Cell systems. 2025:101443. doi:10.1016/j.cels.2025.101443