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Publications

Type 2 Diabetes and Obesity Alter Exercise Training-Induced Transcriptional Adaptations to Subcutaneous White Adipose Tissue.

Middelbeek RJW, Yang J, Nigro P, et al. Type 2 Diabetes and Obesity Alter Exercise Training-Induced Transcriptional Adaptations to Subcutaneous White Adipose Tissue. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.11.681273

PMCID

PMC12632298

ZMYND11 Restrains KMT2A to Enable a Neuronal Developmental Program.

Greben AW, Wu XS, Robb JE, et al. ZMYND11 Restrains KMT2A to Enable a Neuronal Developmental Program. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.31.685692

PMCID

PMC12636335

Transcriptional condensates at super-enhancers mediate pH-dependent transcriptional control in innate immunity.

Wang S, Wu Z, Zhong Z, Zhou X, Zang C. Transcriptional condensates at super-enhancers mediate pH-dependent transcriptional control in innate immunity. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.29.685293

PMCID

PMC12636582

The proton motive force maintains mtDNA euploidy by balancing mtDNA replication with cell proliferation.

Rath SP, Mootha VK. The proton motive force maintains mtDNA euploidy by balancing mtDNA replication with cell proliferation. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.27.684790

PMCID

PMC12636550

Diploid donor-specific assembly enhances somatic structural variant detection in cancer genomes.

Zhang Y, Qu H, Qin Q, Li H, Park PJ. Diploid donor-specific assembly enhances somatic structural variant detection in cancer genomes. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.28.685155

PMCID

PMC12636593

Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor.

Sit B, Sanderlin AG, Zhu CY, Bird LE, Doench JG, Lamason RL. Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.28.684717

PMCID

PMC12636401

An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference.

Alemu R, Terskaya A, Howell M, et al. An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference. Research square. 2025. doi:10.21203/rs.3.rs-7828579/v1

PMCID

PMC12633171

Whole body MondoA deletion protects against diet-induced obesity through uncontrolled multi-organ substrate utilization and futile cycling.

Berger JH, Lau AN, James LC, et al. Whole body MondoA deletion protects against diet-induced obesity through uncontrolled multi-organ substrate utilization and futile cycling. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.06.680559

PMCID

PMC12632559

Adaptation of the multiplexed CRISPR-Cas13 CARMEN RVP assay for longitudinal detection of respiratory pathogens from air samples.

Ellis AL, Stauss M, Tiburcio PB, et al. Adaptation of the multiplexed CRISPR-Cas13 CARMEN RVP assay for longitudinal detection of respiratory pathogens from air samples. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.10.21.25338488

PMCID

PMC12633622

Preselection CD4CD8 thymocytes modulate TCR responsiveness following TCRβ selection.

Kim EJY, Aylard DA, Steier Z, et al. Preselection CD4CD8 thymocytes modulate TCR responsiveness following TCRβ selection. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.10.03.680384

PMCID

PMC12632616