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Publications

Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders.

Streit F, Awasthi S, Hall AS, et al. Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2024.11.12.24316957

Steroid hormone biosynthesis and dietary related metabolites associated with excessive daytime sleepiness.

Faquih T, Potts KS, Nagarajan P, et al. Steroid hormone biosynthesis and dietary related metabolites associated with excessive daytime sleepiness. EBioMedicine. 2025;119:105881. doi:10.1016/j.ebiom.2025.105881

Computer vision detects covert voluntary facial movements in unresponsive brain injury patients.

Cheng X, Swarna S, Robertson J, et al. Computer vision detects covert voluntary facial movements in unresponsive brain injury patients. Communications medicine. 2025;5(1):361. doi:10.1038/s43856-025-01042-y

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors.

Singh S, Gleason CE, Fang M, et al. Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors. Nature. 2025. doi:10.1038/s41586-025-09433-w

Structural basis for the dynamic regulation of mTORC1 by amino acids.

Valenstein ML, Wranik M, Lalgudi P V, et al. Structural basis for the dynamic regulation of mTORC1 by amino acids. Nature. 2025. doi:10.1038/s41586-025-09428-7

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy.

Baruch EN, Gleber-Netto FO, Nagarajan P, et al. Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy. Nature. 2025. doi:10.1038/s41586-025-09370-8

Epigenetic De-repression of PROX1 Promotes Neuroendocrine Prostate Cancer Progression.

Venkadakrishnan VB, Presser A, Voss NCE, et al. Epigenetic De-repression of PROX1 Promotes Neuroendocrine Prostate Cancer Progression. Cancer research. 2025. doi:10.1158/0008-5472.CAN-25-0636

Phenome-wide association study of male and female sex chromosome trisomies in 1.5 million participants of MVP, FinnGen, and UK Biobank.

Davis SM, Liu A, Teerlink CC, et al. Phenome-wide association study of male and female sex chromosome trisomies in 1.5 million participants of MVP, FinnGen, and UK Biobank. American journal of human genetics. 2025;112(9):2088-2101. doi:10.1016/j.ajhg.2025.07.017

"Loss of function in protein Z (PROZ) is associated with increased risk of ischemic stroke in the UK Biobank": reply.

Haj AK, Bendapudi PK. "Loss of function in protein Z (PROZ) is associated with increased risk of ischemic stroke in the UK Biobank": reply. Journal of thrombosis and haemostasis : JTH. 2025;23(9):3009-3010. doi:10.1016/j.jtha.2025.05.019

Highly specific intracellular ubiquitination of a small molecule.

Li W, Garcia-Rivera EM, Mitchell DC, et al. Highly specific intracellular ubiquitination of a small molecule. Nature chemical biology. 2025. doi:10.1038/s41589-025-02011-1