Roh H, Shen S, Hu Y, et al. Coupling CRISPR scanning with targeted chromatin accessibility profiling using a double-stranded DNA deaminase. Nature methods. 2025. doi:10.1038/s41592-025-02811-2
Publications
Karczewski K, Gupta R, Kanai M, et al. Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects. Nature genetics. 2025. doi:10.1038/s41588-025-02335-7
Chen X, Hwang H, Li B, et al. Nuclear receptor coregulator NRIP1 R448G modulates T cell gut homing to control intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(38):e2508269122. doi:10.1073/pnas.2508269122
Das D, Hirayama S, Aye L, et al. Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection. Journal of the National Cancer Institute. 2025. doi:10.1093/jnci/djaf249
Kambhampati S, D’Alessio L, Grab F, et al. TissueMosaic: Self-supervised learning of tissue representations enables differential spatial transcriptomics across samples. Cell systems. 2025;16(9):101394. doi:10.1016/j.cels.2025.101394
Du S. TIGER: A tdTomato in vivo genome-editing reporter mouse for investigating precision-editor delivery approaches. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(35):e2506257122. doi:10.1073/pnas.2506257122
Parsons HA, Messer C, Santos K, et al. Detection of heterogeneous resistance mechanisms to tyrosine kinase inhibitors from cell-free DNA. Cell genomics. 2025:100987. doi:10.1016/j.xgen.2025.100987
Roseman SA, Siegenfeld AP, Lee C, Lue NZ, Waterbury AL, Liau BB. DNA methylation insulates genic regions from CTCF loops near nuclear speckles. eLife. 2025;13. doi:10.7554/eLife.102930
Liu Z, Zhang S, James BT, et al. Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience. Cell. 2025;188(18):4980-5002.e29. doi:10.1016/j.cell.2025.06.031
Khetan S, Carroll BS, Bulyk ML. Multiple overlapping binding sites determine transcription factor occupancy. Nature. 2025. doi:10.1038/s41586-025-09472-3