ӳ��ý

Publications

Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma.

Yang J, Wang C, Fu D, et al. Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma. Nature communications. 2025;16(1):8151. doi:10.1038/s41467-025-62878-5

Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions.

Kotliar D, Curtis M, Agnew R, et al. Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions. Nature methods. 2025. doi:10.1038/s41592-025-02793-1

Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis.

Haj AK, Paul DS, Jurgens SJ, et al. Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis. Nature communications. 2025;16(1):8176. doi:10.1038/s41467-025-62789-5

Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data.

Li R, Alberge JB, Keshavarzian T, et al. Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data. Briefings in bioinformatics. 2025;26(5). doi:10.1093/bib/bbaf516

A Multimodal Imaging Framework to Advance Phenotyping of Living Label-free Breast Cancer Cells.

Bianchi L, Bresci A, Kobayashi-Kirschvink KJ, et al. A Multimodal Imaging Framework to Advance Phenotyping of Living Label-free Breast Cancer Cells. Journal of visualized experiments : JoVE. 2025;(222). doi:10.3791/68498

Childhood Cancer Predisposition and Evolutionary Constraints: Novel lessons from Germline Genomes from 1,127 Children with Cancer.

Stoltze UK, Hansen T van O, Foss-Skiftesvik J, et al. Childhood Cancer Predisposition and Evolutionary Constraints: Novel lessons from Germline Genomes from 1,127 Children with Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025. doi:10.1158/1078-0432.CCR-25-0153

The evolution of health data ecosystems: An international survey.

Lerner-Ellis JP, Price M, Subhani S, et al. The evolution of health data ecosystems: An international survey. American journal of human genetics. 2025;112(8):1769-1777. doi:10.1016/j.ajhg.2025.06.017

Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses.

Nielsen TT, Bali P, Grove J, et al. Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA psychiatry. 2025;82(8):790-800. doi:10.1001/jamapsychiatry.2025.0828

X-linked competition - implications for human development and disease.

Boone PM, Buenaventura T, King JWD, Merkenschlager M. X-linked competition - implications for human development and disease. Nature reviews. Genetics. 2025;26(8):571-580. doi:10.1038/s41576-025-00840-3

Spatial transcriptomics reveals human cortical layer and area specification.

Qian X, Coleman K, Jiang S, et al. Spatial transcriptomics reveals human cortical layer and area specification. Nature. 2025;644(8075):153-163. doi:10.1038/s41586-025-09010-1