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Publications

53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer.

Sun Y, Patterson-Fortin J, Han S, et al. 53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer. Nature communications. 2024;15(1):6676. doi:10.1038/s41467-024-50999-2

Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media.

Bizaki-Vallaskangas A, Rämö J, Sliz E, et al. Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media. Scientific reports. 2024;14(1):18344. doi:10.1038/s41598-024-68781-1

Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials.

Marston NA, Pirruccello JP, Melloni GEM, et al. Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials. Nature medicine. 2024. doi:10.1038/s41591-024-03188-z

DNA-sensing inflammasomes cause recurrent atherosclerotic stroke.

Cao J, Roth S, Zhang S, et al. DNA-sensing inflammasomes cause recurrent atherosclerotic stroke. Nature. 2024. doi:10.1038/s41586-024-07803-4

Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma.

Tsiami F, Lago C, Pozza N, et al. Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma. Acta neuropathologica communications. 2024;12(1):125. doi:10.1186/s40478-024-01831-x

The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort.

Singh SD, Rivier CA, Papier K, et al. The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort. Frontiers in psychiatry. 2024;15:1373797. doi:10.3389/fpsyt.2024.1373797

Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media.

Bizaki-Vallaskangas A, Rämö J, Sliz E, et al. Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media. Scientific reports. 2024;14(1):18344. doi:10.1038/s41598-024-68781-1

Deep Learning-based Modeling for Preclinical Drug Safety Assessment.

Jaume G, de Brot S, Song AH, et al. Deep Learning-based Modeling for Preclinical Drug Safety Assessment. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.07.20.604430

Deep Learning-based Modeling for Preclinical Drug Safety Assessment.

Jaume G, de Brot S, Song AH, et al. Deep Learning-based Modeling for Preclinical Drug Safety Assessment. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.07.20.604430

Deciphering the genetics and mechanisms of predisposition to multiple myeloma.

Went M, Duran-Lozano L, Halldorsson GH, et al. Deciphering the genetics and mechanisms of predisposition to multiple myeloma. Nature communications. 2024;15(1):6644. doi:10.1038/s41467-024-50932-7