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Publications

The Psychiatric Genomics Consortium: discoveries and directions.

Agrawal A, Bulik CM, Abebe DS, et al. The Psychiatric Genomics Consortium: discoveries and directions. The lancet. Psychiatry. 2025;12(8):600-610. doi:10.1016/S2215-0366(25)00124-5

Medications and Risk for Microscopic Colitis: A Nationwide Study of Older Adults in Sweden.

Khalili H, McGee EE, Challa PK, et al. Medications and Risk for Microscopic Colitis: A Nationwide Study of Older Adults in Sweden. Annals of internal medicine. 2025;178(8):1106-1115. doi:10.7326/ANNALS-25-00268

Clusterin drives myeloid bias in aged hematopoietic stem cells by regulating mitochondrial function.

Sun N, Lin CH, Li MY, et al. Clusterin drives myeloid bias in aged hematopoietic stem cells by regulating mitochondrial function. Nature aging. 2025;5(8):1510-1527. doi:10.1038/s43587-025-00908-z

Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids.

Miao Y, Pek NM, Tan C, et al. Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids. Cell. 2025;188(16):4295-4313.e27. doi:10.1016/j.cell.2025.05.041

AI-enabled drug discovery reaches clinical milestone.

Zitnik M. AI-enabled drug discovery reaches clinical milestone. Nature medicine. 2025;31(8):2490-2491. doi:10.1038/s41591-025-03832-2

Informatics at the Frontier of Cancer Research.

Noller K, Botsis T, Camara PG, et al. Informatics at the Frontier of Cancer Research. Cancer research. 2025;85(16):2967-2986. doi:10.1158/0008-5472.CAN-24-2829

Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.

Yammine KM, Abularach SM, Xiong M, et al. Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis. The Journal of biological chemistry. 2025;301(8):110436. doi:10.1016/j.jbc.2025.110436

Advances, challenges, and opportunities of human midbrain organoids for modelling of the dopaminergic system.

Fiorenzano A, Sozzi E, Kastli R, et al. Advances, challenges, and opportunities of human midbrain organoids for modelling of the dopaminergic system. The EMBO journal. 2025;44(15):4181-4195. doi:10.1038/s44318-025-00494-1

Importance of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD.

Bhattacharya R, Marnell CS, Cho SMJ, et al. Importance of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD. Circulation. Genomic and precision medicine. 2025;18(4):e004937. doi:10.1161/CIRCGEN.124.004937

Carriers Multimerize STING Protein Fragments to Activate Type I Interferon Signaling in STING-Deficient Cancer Cells.

Kaskow JA, Hammond PT. Carriers Multimerize STING Protein Fragments to Activate Type I Interferon Signaling in STING-Deficient Cancer Cells. Molecular pharmaceutics. 2025;22(8):4632-4650. doi:10.1021/acs.molpharmaceut.5c00226