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Publications

Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs.

Bizzotto S, Talukdar M, Stronge EA, et al. Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(29):e2509622122. doi:10.1073/pnas.2509622122

Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.

Liu J, Tran D, Xue L, et al. Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy. Nature genetics. 2025. doi:10.1038/s41588-025-02250-x

Electrocardiogram-Based Artificial Intelligence to Identify Coronary Artery Disease.

Kany S, Friedman SF, Al-Alusi M, et al. Electrocardiogram-Based Artificial Intelligence to Identify Coronary Artery Disease. JACC. Advances. 2025;4(9):102041. doi:10.1016/j.jacadv.2025.102041

Marked heterogeneity in malaria infection rate in a Malian longitudinal cohort.

LaVerriere E, Johnson ZM, Shieh M, et al. Marked heterogeneity in malaria infection rate in a Malian longitudinal cohort. Nature communications. 2025;16(1):6512. doi:10.1038/s41467-025-61462-1

A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.

Apfelbaum AA, Morin E, Sturm D, et al. A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas. Nature communications. 2025;16(1):7018. doi:10.1038/s41467-025-61820-z

High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissues.

Haines M, Thorup JR, Gohsman S, et al. High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissues. Molecular & cellular proteomics : MCP. 2025:101044. doi:10.1016/j.mcpro.2025.101044

Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures.

Satpathy S, Clark NM, Chen YJ, et al. Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures. Cancer cell. 2025. doi:10.1016/j.ccell.2025.07.011

Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense.

Barilla RM, Berard C, Sun L, et al. Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense. Science (New York, N.Y.). 2025;389(6757):260-267. doi:10.1126/science.adn9850

In vivo prime editing rescues alternating hemiplegia of childhood in mice.

Sousa AA, Terrey M, Sakai HA, et al. In vivo prime editing rescues alternating hemiplegia of childhood in mice. Cell. 2025. doi:10.1016/j.cell.2025.06.038

Single-cell image-based screens identify host regulators of Ebola virus infection dynamics.

Carlson RJ, Patten JJ, Stefanakis G, et al. Single-cell image-based screens identify host regulators of Ebola virus infection dynamics. Nature microbiology. 2025. doi:10.1038/s41564-025-02034-3