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Publications

A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma.

Blass E, Keskin DB, Tu CR, et al. A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma. Cell. 2025. doi:10.1016/j.cell.2025.06.019

Mechanical underwater adhesive devices for soft substrates.

Kang Z, Gomez JA, Ross AM, et al. Mechanical underwater adhesive devices for soft substrates. Nature. 2025. doi:10.1038/s41586-025-09304-4

Combining phenomics with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion.

Tegtmeyer M, Liyanage D, Han Y, et al. Combining phenomics with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion. Nature communications. 2025;16(1):6332. doi:10.1038/s41467-025-61547-x

Precisely defining disease variant effects in CRISPR-edited single cells.

Baglaenko Y, Mu Z, Curtis M, et al. Precisely defining disease variant effects in CRISPR-edited single cells. Nature. 2025. doi:10.1038/s41586-025-09313-3

Phosphorylation-Inducing Molecules for Regulating Dynamic Cellular Processes.

Pergu R, Sreekanth V, Kokkonda P, et al. Phosphorylation-Inducing Molecules for Regulating Dynamic Cellular Processes. Journal of the American Chemical Society. 2025;147(29):25316-25324. doi:10.1021/jacs.5c04275

Bering: joint cell segmentation and annotation for spatial transcriptomics with transferred graph embeddings.

Jin K, Zhang Z, Zhang K, et al. Bering: joint cell segmentation and annotation for spatial transcriptomics with transferred graph embeddings. Nature communications. 2025;16(1):6618. doi:10.1038/s41467-025-60898-9

Regulation of inflammatory responses by pH-dependent transcriptional condensates.

Wu Z, Pope SD, Ahmed NS, et al. Regulation of inflammatory responses by pH-dependent transcriptional condensates. Cell. 2025. doi:10.1016/j.cell.2025.06.033

Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.

Wang Z, Skwarska A, Poigaialwar G, et al. Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML. Blood. 2025;146(3):341-355. doi:10.1182/blood.2024027117

The Somatic Mosaicism across Human Tissues Network.

Coorens THH, Oh JW, Choi YA, et al. The Somatic Mosaicism across Human Tissues Network. Nature. 2025;643(8070):47-59. doi:10.1038/s41586-025-09096-7

FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses.

Kim C, Gabriel KR, Boone D, et al. FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses. Science advances. 2025;11(27):eadu9104. doi:10.1126/sciadv.adu9104