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Publications

Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis.

Merz M, Shoba V, Pergu R, et al. Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.13.659082

Small molecule modulators of TOX protein re-invigorate T cell activity.

Wu B, Chang H, Singh P, et al. Small molecule modulators of TOX protein re-invigorate T cell activity. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.03.03.641115

Optimizing participant and community engagement in cancer genomic sequencing research.

Crossnohere NL, Schuster ALR, Blair CK, et al. Optimizing participant and community engagement in cancer genomic sequencing research. Genetics in medicine : official journal of the American College of Medical Genetics. 2025;27(9):101483. doi:10.1016/j.gim.2025.101483

Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions.

Andersen BM, Akl CF, Wheeler MA, et al. Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions. Nature. 2025. doi:10.1038/s41586-025-09191-9

Single-cell and spatiotemporal profile of ovulation in the mouse ovary.

Huang R, Kratka CE, Pea J, et al. Single-cell and spatiotemporal profile of ovulation in the mouse ovary. PLoS biology. 2025;23(6):e3003193. doi:10.1371/journal.pbio.3003193

Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants.

Revach OY, Cicerchia AM, Shorer O, et al. Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants. Cell reports. Medicine. 2025:102210. doi:10.1016/j.xcrm.2025.102210

Characterization of spatial homogeneous regions in tissues with concordex.

Jackson KC, Booeshaghi S, Gálvez-Merchán Á, et al. Characterization of spatial homogeneous regions in tissues with concordex. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2023.06.28.546949

Incorporating genetic data improves target trial emulations and informs the use of polygenic scores in randomized controlled trial design.

German J, Yang Z, Urbut S, et al. Incorporating genetic data improves target trial emulations and informs the use of polygenic scores in randomized controlled trial design. Nature genetics. 2025. doi:10.1038/s41588-025-02229-8

Reciprocal interaction between cortical SST and PV interneurons in top-down regulation of retinothalamic refinement.

Jiang Q, Wu SJ, Fishell G, Chen C. Reciprocal interaction between cortical SST and PV interneurons in top-down regulation of retinothalamic refinement. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(25):e2504224122. doi:10.1073/pnas.2504224122

ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome.

Clarke TL, Cho HM, Ceppi I, et al. ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome. Nature cell biology. 2025;27(6):1006-1020. doi:10.1038/s41556-025-01674-1