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Publications

Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4 T cell response.

Chudnovskiy A, Castro TBR, Nakandakari-Higa S, et al. Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4 T cell response. Science immunology. 2024;9(100):eadq8843. doi:10.1126/sciimmunol.adq8843

A Bayesian framework for inferring dynamic intercellular interactions from time-series single-cell data.

Park C, Mani S, Beltran-Velez N, et al. A Bayesian framework for inferring dynamic intercellular interactions from time-series single-cell data. Genome research. 2024. doi:10.1101/gr.279126.124

Pervasive mislocalization of pathogenic coding variants underlying human disorders.

Lacoste J, Haghighi M, Haider S, et al. Pervasive mislocalization of pathogenic coding variants underlying human disorders. Cell. 2024. doi:10.1016/j.cell.2024.09.003

Equimolar Cross-Coupling Using Reactive Coiled Coils for Covalent Protein Assemblies.

Takeuchi H, Shimshoni E, Gandhesiri S, Loas A, Pentelute BL. Equimolar Cross-Coupling Using Reactive Coiled Coils for Covalent Protein Assemblies. Bioconjugate chemistry. 2024. doi:10.1021/acs.bioconjchem.4c00327

Compromised CDK12 activity causes dependency on the high activity of O-GlcNAc transferase.

Pallasaho S, Gondane A, Kutz J, et al. Compromised CDK12 activity causes dependency on the high activity of O-GlcNAc transferase. Glycobiology. 2024. doi:10.1093/glycob/cwae081

Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa.

Fihn CA, Lembke HK, Gaulin J, et al. Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa. Bioorganic chemistry. 2024;153:107840. doi:10.1016/j.bioorg.2024.107840

Cross-ancestry analysis of brain QTLs enhances interpretation of schizophrenia genome-wide association studies.

Chen Y, Liu S, Ren Z, et al. Cross-ancestry analysis of brain QTLs enhances interpretation of schizophrenia genome-wide association studies. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.09.001

Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.

Hawkes G, Beaumont RN, Li Z, et al. Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. Nature communications. 2024;15(1):8549. doi:10.1038/s41467-024-52579-w

Population-specific putative causal variants shape quantitative traits.

Koyama S, Liu X, Koike Y, et al. Population-specific putative causal variants shape quantitative traits. Nature genetics. 2024. doi:10.1038/s41588-024-01913-5

Tyche: Stochastic In-Context Learning for Medical Image Segmentation

Rakic M, Wong HE, Ortiz JJG, Cimini B, Guttag J, Dalca AV. Tyche: Stochastic In-Context Learning for Medical Image Segmentation. In: IEEE CVF Computer Vision and Pattern Recognition Conference (CVPR). arXiv; 2024. doi:10.48550/arXiv.2401.13650