Anvar NE, Lin C, Ma X, et al. Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform. Nature communications. 2024;15(1):3577. doi:10.1038/s41467-024-47795-3
Publications
Lampson BL, Ramίrez AS, Baro M, et al. Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB. Cell. 2024;187(9):2209-2223.e16. doi:10.1016/j.cell.2024.03.022
Guo B, Liu T, Choi S, et al. Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice. Cell reports. Medicine. 2024:101534. doi:10.1016/j.xcrm.2024.101534
Chen Z, Guo X, Tao R, et al. Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes. Nature communications. 2024;15(1):3557. doi:10.1038/s41467-024-47399-x
Purdue MP, Dutta D, Machiela MJ, et al. Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nature genetics. 2024. doi:10.1038/s41588-024-01725-7
Guo B, Liu T, Choi S, et al. Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice. Cell reports. Medicine. 2024:101534. doi:10.1016/j.xcrm.2024.101534
Mandla R, Schroeder P, Porneala B, et al. Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study. Genome medicine. 2024;16(1):63. doi:10.1186/s13073-024-01337-0
Ho CLC, Gilbert MB, Urtecho G, et al. Stool protein mass spectrometry identifies biomarkers for the early detection of diffuse-type gastric cancer. Cancer prevention research (Philadelphia, Pa.). 2024. doi:10.1158/1940-6207.CAPR-23-0449
Giglio RM, Hou N, Wyatt A, et al. A heterogeneous pharmaco-transcriptomic landscape induced by targeting a single oncogenic kinase. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.04.08.587960
Chen Y, Dawes R, Kim HC, et al. variants in the non-coding spliceosomal snRNA gene are a frequent cause of syndromic neurodevelopmental disorders. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.04.07.24305438