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Publications

Explainable modeling of single-cell perturbation data using attention and sparse dictionary learning.

Xu Y, Fleming S, Tegtmeyer M, McCarroll SA, Babadi M. Explainable modeling of single-cell perturbation data using attention and sparse dictionary learning. Cell systems. 2025:101245. doi:10.1016/j.cels.2025.101245

Variant-to-function approaches for adipose tissue: Insights into cardiometabolic disorders.

Metz S, Belanich JR, Claussnitzer M, Kilpeläinen TO. Variant-to-function approaches for adipose tissue: Insights into cardiometabolic disorders. Cell genomics. 2025:100844. doi:10.1016/j.xgen.2025.100844

Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody.

Rao V, Sapse I, Cohn H, et al. Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.03.07.642041

Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody.

Rao V, Sapse I, Cohn H, et al. Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.03.07.642041

Inverted Alu repeats in loop-out exon skipping across hominoid evolution.

Denisko D, Kim J, Ku J, Zhao B, Lee EA. Inverted Alu repeats in loop-out exon skipping across hominoid evolution. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.03.07.642063

Inverted Alu repeats in loop-out exon skipping across hominoid evolution.

Denisko D, Kim J, Ku J, Zhao B, Lee EA. Inverted Alu repeats in loop-out exon skipping across hominoid evolution. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.03.07.642063

AOC 1044 induces exon 44 skipping and restores dystrophin protein in preclinical models of Duchenne muscular dystrophy.

Etxaniz U, Marks I, Albin T, et al. AOC 1044 induces exon 44 skipping and restores dystrophin protein in preclinical models of Duchenne muscular dystrophy. Nucleic acids research. 2025;53(6). doi:10.1093/nar/gkaf241

AOC 1044 induces exon 44 skipping and restores dystrophin protein in preclinical models of Duchenne muscular dystrophy.

Etxaniz U, Marks I, Albin T, et al. AOC 1044 induces exon 44 skipping and restores dystrophin protein in preclinical models of Duchenne muscular dystrophy. Nucleic acids research. 2025;53(6). doi:10.1093/nar/gkaf241

Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care.

Kreienkamp RJ, Deutsch AJ, Huerta-Chagoya A, et al. Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.03.06.25323229

Non-relapse mortality with bispecific antibodies: A systematic review and meta-analysis in lymphoma and multiple myeloma.

Tix T, Alhomoud M, Shouval R, et al. Non-relapse mortality with bispecific antibodies: A systematic review and meta-analysis in lymphoma and multiple myeloma. Molecular therapy : the journal of the American Society of Gene Therapy. 2025. doi:10.1016/j.ymthe.2025.03.048