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Publications

LAVASET: Latent variable stochastic ensemble of trees. An ensemble method for correlated datasets with spatial, spectral, and temporal dependencies.

Kasapi M, Xu K, Ebbels TMD, O’Regan DP, Ware JS, Posma JM. LAVASET: Latent variable stochastic ensemble of trees. An ensemble method for correlated datasets with spatial, spectral, and temporal dependencies. Bioinformatics (Oxford, England). 2024. doi:10.1093/bioinformatics/btae101

Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation.

Faro VL, Bhattacharya A, Zhou W, et al. Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation. Cell reports. Medicine. 2024;5(2):101430. doi:10.1016/j.xcrm.2024.101430

Learning representations for image-based profiling of perturbations.

Moshkov N, Bornholdt M, Benoit S, et al. Learning representations for image-based profiling of perturbations. Nature communications. 2024;15(1):1594. doi:10.1038/s41467-024-45999-1

WNT signalling control by KDM5C during development affects cognition.

Karwacki-Neisius V, Jang A, Cukuroglu E, et al. WNT signalling control by KDM5C during development affects cognition. Nature. 2024. doi:10.1038/s41586-024-07067-y

Author Correction: An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB.

Min J, Zaslavsky A, Fedele G, et al. Author Correction: An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB. Nature medicine. 2024. doi:10.1038/s41591-024-02866-2

Temporal dynamics of gut microbiomes in non-industrialized urban Amazonia.

Schaan AP, Vidal A, Zhang AN, et al. Temporal dynamics of gut microbiomes in non-industrialized urban Amazonia. mSystems. 2024:e0070723. doi:10.1128/msystems.00707-23

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

Suzuki K, Hatzikotoulas K, Southam L, et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. 2024. doi:10.1038/s41586-024-07019-6

VIBRANT: spectral profiling for single-cell drug responses.

Liu X, Shi L, Zhao Z, Shu J, Min W. VIBRANT: spectral profiling for single-cell drug responses. Nature methods. 2024. doi:10.1038/s41592-024-02185-x

The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.

Sumida TS, Cheru NT, Hafler DA. The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases. Nature reviews. Immunology. 2024. doi:10.1038/s41577-024-00994-x

Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.

Lennon NJ, Kottyan LC, Kachulis C, et al. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature medicine. 2024. doi:10.1038/s41591-024-02796-z