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Publications

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.

Yuan K, Longchamps RJ, Pardiñas AF, et al. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. Nature genetics. 2024. doi:10.1038/s41588-024-01870-z

Diffusion barriers imposed by tissue topology shape Hedgehog morphogen gradients.

Schlissel G, Meziane M, Narducci D, Hansen AS, Li P. Diffusion barriers imposed by tissue topology shape Hedgehog morphogen gradients. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(36):e2400677121. doi:10.1073/pnas.2400677121

Bacterial strain sharing between humans, animals, and the environment among urban households.

Kim DD, Swarthout JM, Worby CJ, et al. Bacterial strain sharing between humans, animals, and the environment among urban households. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.08.05.24311509

A foundation model for clinician-centered drug repurposing.

Huang K, Chandak P, Wang Q, et al. A foundation model for clinician-centered drug repurposing. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2023.03.19.23287458

Scalable imaging-free spatial genomics through computational reconstruction.

Hu C, Borji M, Marrero GJ, et al. Scalable imaging-free spatial genomics through computational reconstruction. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.08.05.606465

Improved high quality sand fly assemblies enabled by ultra low input long read sequencing.

Huang M, Kingan S, Shoue D, et al. Improved high quality sand fly assemblies enabled by ultra low input long read sequencing. Scientific data. 2024;11(1):918. doi:10.1038/s41597-024-03628-y

A Two-Sample Mendelian Randomization Study of Neuroticism and Sleep Bruxism.

Strausz T, Strausz S, Jones SE, et al. A Two-Sample Mendelian Randomization Study of Neuroticism and Sleep Bruxism. Journal of dental research. 2024:220345241264749. doi:10.1177/00220345241264749

All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for under-represented populations.

Tsuo K, Shi Z, Ge T, et al. All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for under-represented populations. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.08.06.606846

Genome-wide fine-mapping improves identification of causal variants.

Wu Y, Zheng Z, Thibaut L, et al. Genome-wide fine-mapping improves identification of causal variants. Research square. 2024. doi:10.21203/rs.3.rs-4759390/v1

Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes.

Wu SJ, Dai M, Yang SP, et al. Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes. Research square. 2024. doi:10.21203/rs.3.rs-4774421/v1