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Publications

SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.

Haltom J, Trovão NS, Guarnieri J, et al. SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.11.27.23298847

Benchmarking computational methods to identify spatially variable genes and peaks.

Li Z, Patel ZM, Song D, Yan G, Li JJ, Pinello L. Benchmarking computational methods to identify spatially variable genes and peaks. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.12.02.569717

Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events.

Heyne HO, Pajuste FD, Wanner J, et al. Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events. medRxiv : the preprint server for health sciences. 2023. doi:10.1101/2023.11.27.23297542

Simultaneous CRISPR screening and spatial transcriptomics reveals intracellular, intercellular, and functional transcriptional circuits.

Binan L, Danquah S, Valakh V, et al. Simultaneous CRISPR screening and spatial transcriptomics reveals intracellular, intercellular, and functional transcriptional circuits. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.11.30.569494

Cross-species and tissue imputation of species-level DNA methylation samples across mammalian species.

Maciejewski E, Horvath S, Ernst J. Cross-species and tissue imputation of species-level DNA methylation samples across mammalian species. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.11.26.568769

Neotelomeres and Telomere-Spanning Chromosomal Arm Fusions in Cancer Genomes Revealed by Long-Read Sequencing.

Tan KT, Slevin MK, Leibowitz ML, Garrity-Janger M, Li H, Meyerson M. Neotelomeres and Telomere-Spanning Chromosomal Arm Fusions in Cancer Genomes Revealed by Long-Read Sequencing. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.11.30.569101

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival.

Tzouanas CN, Sherman MS, Shay JES, et al. Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.11.30.569407

Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties.

Cooney AL, Brommel CM, Traore S, et al. Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties. Frontiers in genome editing. 2023;5:1271813. doi:10.3389/fgeed.2023.1271813

Identification of drug candidates targeting monocyte reprogramming in people living with HIV.

Knoll R, Bonaguro L, Santos JCD, et al. Identification of drug candidates targeting monocyte reprogramming in people living with HIV. Frontiers in immunology. 2023;14:1275136. doi:10.3389/fimmu.2023.1275136

Assessment of treatment response in cardiac sarcoidosis based on myocardial F-FDG uptake.

Frischknecht L, Schaab J, Schmauch E, et al. Assessment of treatment response in cardiac sarcoidosis based on myocardial F-FDG uptake. Frontiers in immunology. 2023;14:1286684. doi:10.3389/fimmu.2023.1286684