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Publications

JOINTLY: interpretable joint clustering of single-cell transcriptomes.

Møller AF, Madsen JGS. JOINTLY: interpretable joint clustering of single-cell transcriptomes. Nature communications. 2023;14(1):8473. doi:10.1038/s41467-023-44279-8

Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7.

Kann MC, Schneider EM, Almazan AJ, et al. Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7. Leukemia. 2023. doi:10.1038/s41375-023-02113-6

Identifying metabolic features of colorectal cancer liability using Mendelian randomization.

Bull C, Hazelwood E, Bell JA, et al. Identifying metabolic features of colorectal cancer liability using Mendelian randomization. eLife. 2023;12. doi:10.7554/eLife.87894

Autonomous, multiproperty-driven molecular discovery: From predictions to measurements and back.

Koscher BA, Canty RB, McDonald MA, et al. Autonomous, multiproperty-driven molecular discovery: From predictions to measurements and back. Science (New York, N.Y.). 2023;382(6677):eadi1407. doi:10.1126/science.adi1407

Neurosurgery elucidates somatic mutations.

Maury EA, Walsh CA, Kahle KT. Neurosurgery elucidates somatic mutations. Science (New York, N.Y.). 2023;382(6677):1360-1362. doi:10.1126/science.adj2244

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus.

Singh AK, Allington G, Viviano S, et al. A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus. Brain : a journal of neurology. 2023. doi:10.1093/brain/awad405

Revisiting chromatin packaging in mouse sperm.

Yin Q, Yang CH, Strelkova OS, et al. Revisiting chromatin packaging in mouse sperm. Genome research. 2023;33(12):2079-93. doi:10.1101/gr.277845.123

Chromatin regulator SMARCAL1 modulates cellular lipid metabolism.

Nagai TH, Hartigan C, Mizoguchi T, et al. Chromatin regulator SMARCAL1 modulates cellular lipid metabolism. Communications biology. 2023;6(1):1298. doi:10.1038/s42003-023-05665-6

Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins.

Drouard G, Hagenbeek FA, Whipp AM, et al. Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins. BMC medicine. 2023;21(1):508. doi:10.1186/s12916-023-03198-7

PPARγ agonist treatment reduces fibroadipose tissue in secondary lymphedema by exhausting fibroadipogenic PDGFRα+ mesenchymal cells.

Chen Z, Ghavimi SAA, Wu M, et al. PPARγ agonist treatment reduces fibroadipose tissue in secondary lymphedema by exhausting fibroadipogenic PDGFRα+ mesenchymal cells. JCI insight. 2023;8(24). doi:10.1172/jci.insight.165324